CareDx, Inc (CDNA) vs Dyne Therapeutics, Inc. (DYN)

A side-by-side comparison of CareDx, Inc and Dyne Therapeutics, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

Compare
CareDx, Inc logo
CDNA
CareDx, Inc
$3.58B
$69.13HealthcareDelayed quote: Oct 6, 2026, 10:05 AM EDT
Dyne Therapeutics, Inc. logo
DYN
Dyne Therapeutics, Inc.
$2.83B
$15.16HealthcareDelayed quote: Oct 6, 2026, 10:05 AM EDT

Total return — CDNA vs DYN

growth of $100 · dividends reinvested · last 6y
CDNA +107.0% (+12.9%/yr)DYN -35.4% (-7.0%/yr)CDNA compounded faster over this window
0100200Start $100202120222023202420252026$207$65
CDNA DYN

CDNA vs DYN: by the numbers

  • •CDNA is the larger company ($3.58B vs $2.83B market cap).
  • •CDNA is profitable (24.23% net margin) while DYN runs a net loss (0.00%).

Metrics side by side

Valuation

MetricCDNADYN
P/E ratio33.37N/A
Forward P/E57.71N/A
P/S ratio7.81N/A
P/B ratio8.404.03
EV / EBITDA207.08N/A
FCF yield2.38%N/A

Profitability

MetricCDNADYN
Gross margin70.58%0.00%
Operating margin-0.92%0.00%
Net margin24.23%0.00%
ROE26.08%-73.97%
ROIC-0.93%-58.28%

Growth (annualized)

MetricCDNADYN
Revenue CAGR (5Y)12.56%N/A
Total return CAGR (5Y)1.33%-0.38%

Frequently asked

Is CDNA or DYN more profitable?
CDNA runs the higher net margin — CDNA at 24.23% versus DYN at 0.00%.
How have CDNA and DYN total returns compared?
Over the past 5 years, CDNA delivered 1.33% and DYN delivered -0.38% annualized total return. Past performance doesn't predict future results.

Go deeper

Full CDNA analysisFull DYN analysisInteractive comparison tool

Dig into the metrics

CareDx P/E ratioCareDx ROEDyne Therapeutics ROECareDx operating marginDyne Therapeutics operating marginCareDx revenue growthDyne Therapeutics revenue growthCareDx free cash flowDyne Therapeutics free cash flow

CareDx & Dyne Therapeutics appear in these rankings

Highest ROE StocksHighest 10-Year Total Return Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.