Cardio Diagnostics Holdings, Inc. (CDIO) vs Ensysce Biosciences, Inc. (ENSC)

A side-by-side comparison of Cardio Diagnostics Holdings, Inc. and Ensysce Biosciences, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

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Total return — CDIO vs ENSC

growth of $100 · dividends reinvested · last 5y
CDIO -99.3% (-62.9%/yr)ENSC -100.0% (-87.1%/yr)CDIO compounded faster over this window
Log scale — wide-divergence pair
0001101001kStart $1002023202420252026$1$0
CDIO ENSC

CDIO vs ENSC: by the numbers

  • •ENSC is the larger company ($6M vs $6M market cap).
  • •Both run net losses; ENSC's is the smaller (-1084.23% vs -44771.83% net margin).

Metrics side by side

Valuation

MetricCDIOENSC
P/S ratio421.905.53
P/B ratio0.82N/A

Profitability

MetricCDIOENSC
Gross margin100.00%0.00%
Operating margin-43737.46%0.00%
Net margin-44771.83%-1084.23%
ROE-87.12%N/A
ROIC-82.84%N/A

Growth (annualized)

MetricCDIOENSC
Total return CAGR (5Y)N/A-86.22%

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.