Crescent Biopharma, Inc. (CBIO) vs ProKidney Corp. (PROK)
A side-by-side comparison of Crescent Biopharma, Inc. and ProKidney Corp. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
CBIO
Crescent Biopharma, Inc.
$14.01HealthcareDelayed quote: Oct 6, 2026, 12:20 PM EDT
PROK
ProKidney Corp.
$1.60HealthcareDelayed quote: Oct 6, 2026, 12:14 PM EDT
Total return — CBIO vs PROK
growth of $100 · dividends reinvested · last 5yCBIO -79.0% (-26.8%/yr)PROK -84.4% (-31.0%/yr)CBIO compounded faster over this window
CBIO PROK
CBIO vs PROK: by the numbers
- •PROK is the larger company ($536M vs $520M market cap).
- •Both run net losses; CBIO's is the smaller (-1371.51% vs -10599.76% net margin).
Metrics side by side
Valuation
| Metric | CBIO | PROK |
|---|---|---|
| P/S ratio | 43.79 | 655.65 |
| P/B ratio | 3.27 | N/A |
Profitability
| Metric | CBIO | PROK |
|---|---|---|
| Gross margin | 100.00% | 100.00% |
| Operating margin | -1407.52% | -18477.83% |
| Net margin | -1371.51% | -10599.76% |
| ROE | -99.83% | N/A |
| ROIC | -102.59% | -78.31% |
Growth (annualized)
| Metric | CBIO | PROK |
|---|---|---|
| Revenue CAGR (5Y) | 39.89% | N/A |
| Total return CAGR (5Y) | -24.40% | -30.65% |
Frequently asked
- How have CBIO and PROK total returns compared?
- Over the past 5 years, CBIO delivered -24.40% and PROK delivered -30.65% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Crescent Biopharma ROEProKidney ROECrescent Biopharma operating marginProKidney operating marginCrescent Biopharma revenue growthProKidney revenue growthCrescent Biopharma free cash flowProKidney free cash flow
Crescent Biopharma & ProKidney appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.