Which has the lower trailing P/E, CAI or HSIC?

HSIC has the lower trailing P/E: CAI trades at 84.91 and HSIC at 24.56. P/E is one valuation measure and does not by itself establish which business is cheaper.

Which has grown faster, CAI or HSIC?

Over the past five years, CAI grew revenue faster — CAI at a 26.15% CAGR versus HSIC at 2.71%.

Is CAI or HSIC more profitable?

CAI runs the higher net margin — CAI at 10.62% versus HSIC at 2.96%.

Caris Life Sciences, Inc. (CAI) vs Henry Schein, Inc. (HSIC)

A side-by-side comparison of Caris Life Sciences, Inc. and Henry Schein, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

CAI

Caris Life Sciences, Inc.

$8.59B

$30.39HealthcareDelayed quote: Oct 5, 2026, 4:00 PM EDT

HSIC

Henry Schein, Inc.

$9.60B

$84.23HealthcareDelayed quote: Oct 5, 2026, 4:00 PM EDT

Total return — CAI vs HSIC

growth of $100 · dividends reinvested · last 1y

CAI +8.5% (+8.5%/yr)HSIC +18.4% (+18.4%/yr)HSIC compounded faster over this window

CAI HSIC

CAI vs HSIC: by the numbers

•HSIC is the larger company ($9.60B vs $8.59B market cap).
•HSIC trades at the lower trailing earnings multiple (24.56 vs 84.91 P/E), one valuation lens rather than an overall verdict.
•CAI converts more revenue to profit (10.62% vs 2.96% net margin).
•CAI grew revenue faster over the past five years (26.15% vs 2.71% CAGR).

Metrics side by side

Valuation

Metric	CAI	HSIC
P/E ratio	84.91	24.56
Forward P/E	261.92	15.64
PEG ratio	N/A	7.77
P/S ratio	8.68	0.71
P/B ratio	14.52	3.04
EV / EBITDA	47.99	12.19
FCF yield	1.71%	5.62%

Profitability

Metric	CAI	HSIC
Gross margin	69.66%	30.31%
Operating margin	5.56%	5.69%
Net margin	10.62%	2.96%
ROE	17.77%	12.77%
ROIC	14.76%	6.53%

Growth (annualized)

Metric	CAI	HSIC
Revenue CAGR (5Y)	26.15%	2.71%
EPS CAGR (5Y)	N/A	3.14%
FCF CAGR (5Y)	N/A	0.82%
Total return CAGR (5Y)	N/A	1.39%

Frequently asked

Which has the lower trailing P/E, CAI or HSIC?: HSIC has the lower trailing P/E: CAI trades at 84.91 and HSIC at 24.56. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, CAI or HSIC?: Over the past five years, CAI grew revenue faster — CAI at a 26.15% CAGR versus HSIC at 2.71%.
Is CAI or HSIC more profitable?: CAI runs the higher net margin — CAI at 10.62% versus HSIC at 2.96%.

Go deeper

Full CAI analysis Full HSIC analysis Interactive comparison tool

Dig into the metrics

Caris Life Sciences P/E ratio Henry Schein P/E ratio Caris Life Sciences ROE Henry Schein ROE Caris Life Sciences operating margin Henry Schein operating margin Caris Life Sciences revenue growth Henry Schein revenue growth Caris Life Sciences free cash flow Henry Schein free cash flow

Caris Life Sciences & Henry Schein appear in these rankings

Fastest Revenue Growth Stocks Highest FCF Yield Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.