Candel Therapeutics, Inc. (CADL) vs Wave Life Sciences Ltd. (WVE)
A side-by-side comparison of Candel Therapeutics, Inc. and Wave Life Sciences Ltd. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
CADL
Candel Therapeutics, Inc.
$9.87HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT
WVE
Wave Life Sciences Ltd.
$3.52HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT
Total return — CADL vs WVE
growth of $100 · dividends reinvested · last 5yCADL +46.1% (+7.9%/yr)WVE -31.6% (-7.3%/yr)CADL compounded faster over this window
CADL WVE
CADL vs WVE: by the numbers
- •CADL is the larger company ($723M vs $694M market cap).
- •Both run net losses; CADL's is the smaller (0.00% vs -309.73% net margin).
Metrics side by side
Valuation
| Metric | CADL | WVE |
|---|---|---|
| P/S ratio | N/A | 10.61 |
| P/B ratio | 5.73 | 1.53 |
Profitability
| Metric | CADL | WVE |
|---|---|---|
| Gross margin | 0.00% | 79.28% |
| Operating margin | 0.00% | -504.09% |
| Net margin | 0.00% | -309.73% |
| ROE | -70.19% | -44.64% |
| ROIC | -36.83% | -42.94% |
Growth (annualized)
| Metric | CADL | WVE |
|---|---|---|
| Revenue CAGR (5Y) | N/A | 33.08% |
| Total return CAGR (5Y) | -1.42% | -4.33% |
Frequently asked
- How have CADL and WVE total returns compared?
- Over the past 5 years, CADL delivered -1.42% and WVE delivered -4.33% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Candel Therapeutics ROEWave Life Sciences ROECandel Therapeutics operating marginWave Life Sciences operating marginCandel Therapeutics revenue growthWave Life Sciences revenue growthCandel Therapeutics free cash flowWave Life Sciences free cash flow
Candel Therapeutics & Wave Life Sciences appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.