Candel Therapeutics, Inc. (CADL) vs Gyre Therapeutics, Inc. (GYRE)
A side-by-side comparison of Candel Therapeutics, Inc. and Gyre Therapeutics, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
CADL
Candel Therapeutics, Inc.
$10.16HealthcareDelayed quote: Oct 6, 2026, 12:10 PM EDT
GYRE
Gyre Therapeutics, Inc.
$7.20HealthcareDelayed quote: Oct 6, 2026, 12:09 PM EDT
Total return — CADL vs GYRE
growth of $100 · dividends reinvested · last 5yCADL +46.1% (+7.9%/yr)GYRE -15.6% (-3.3%/yr)CADL compounded faster over this window
CADL GYRE
CADL vs GYRE: by the numbers
- •GYRE is the larger company ($802M vs $745M market cap).
- •Both run net losses; CADL's is the smaller (0.00% vs -14.52% net margin).
Metrics side by side
Valuation
| Metric | CADL | GYRE |
|---|---|---|
| P/S ratio | N/A | 6.72 |
| P/B ratio | 5.90 | 7.43 |
Profitability
| Metric | CADL | GYRE |
|---|---|---|
| Gross margin | 0.00% | 94.30% |
| Operating margin | 0.00% | 9.86% |
| Net margin | 0.00% | -14.52% |
| ROE | -70.19% | -13.30% |
| ROIC | -36.83% | -9.77% |
Growth (annualized)
| Metric | CADL | GYRE |
|---|---|---|
| Revenue CAGR (5Y) | N/A | 84.92% |
| Total return CAGR (5Y) | -1.42% | -0.34% |
Frequently asked
- How have CADL and GYRE total returns compared?
- Over the past 5 years, CADL delivered -1.42% and GYRE delivered -0.34% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Candel Therapeutics ROEGyre Therapeutics ROECandel Therapeutics operating marginGyre Therapeutics operating marginCandel Therapeutics revenue growthGyre Therapeutics revenue growthCandel Therapeutics free cash flowGyre Therapeutics free cash flow
Candel Therapeutics & Gyre Therapeutics appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.