Which has the lower trailing P/E, BLLN or OPCH?

OPCH has the lower trailing P/E: BLLN trades at 161.94 and OPCH at 23.39. P/E is one valuation measure and does not by itself establish which business is cheaper.

Is BLLN or OPCH more profitable?

BLLN runs the higher net margin — BLLN at 8.43% versus OPCH at 3.68%.

BillionToOne, Inc. (BLLN) vs Option Care Health, Inc. (OPCH)

A side-by-side comparison of BillionToOne, Inc. and Option Care Health, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

BLLN

BillionToOne, Inc.

$4.62B

$100.42HealthcareDelayed quote: Oct 6, 2026, 1:00 PM EDT

OPCH

Option Care Health, Inc.

$4.66B

$31.10HealthcareDelayed quote: Oct 6, 2026, 1:00 PM EDT

Total return — BLLN vs OPCH

growth of $100 · dividends reinvested · last 1y

BLLN +0.1% (+0.1%/yr)OPCH -18.5% (-18.5%/yr)BLLN compounded faster over this window

BLLN OPCH

BLLN vs OPCH: by the numbers

•OPCH is the larger company ($4.66B vs $4.62B market cap).
•OPCH trades at the lower trailing earnings multiple (23.39 vs 161.94 P/E), one valuation lens rather than an overall verdict.
•BLLN converts more revenue to profit (8.43% vs 3.68% net margin).

Metrics side by side

Valuation

Metric	BLLN	OPCH
P/E ratio	161.94	23.39
Forward P/E	126.43	16.55
P/S ratio	11.62	0.82
P/B ratio	8.60	3.70
EV / EBITDA	75.79	13.99
FCF yield	0.72%	N/A

Profitability

Metric	BLLN	OPCH
Gross margin	71.27%	18.17%
Operating margin	10.90%	5.94%
Net margin	8.43%	3.68%
ROE	6.24%	16.63%
ROIC	6.39%	9.68%

Growth (annualized)

Metric	BLLN	OPCH
Revenue CAGR (5Y)	N/A	12.17%
Total return CAGR (5Y)	N/A	-1.37%

Frequently asked

Which has the lower trailing P/E, BLLN or OPCH?: OPCH has the lower trailing P/E: BLLN trades at 161.94 and OPCH at 23.39. P/E is one valuation measure and does not by itself establish which business is cheaper.
Is BLLN or OPCH more profitable?: BLLN runs the higher net margin — BLLN at 8.43% versus OPCH at 3.68%.

Go deeper

Full BLLN analysis Full OPCH analysis Interactive comparison tool

Dig into the metrics

BillionToOne P/E ratio Option Care Health P/E ratio BillionToOne ROE Option Care Health ROE BillionToOne operating margin Option Care Health operating margin BillionToOne revenue growth Option Care Health revenue growth BillionToOne free cash flow Option Care Health free cash flow

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.