Which has grown faster, BIIB or MRNA?

Over the past five years, MRNA grew revenue faster — BIIB at a -4.80% CAGR versus MRNA at -2.60%.

Is BIIB or MRNA more profitable?

BIIB runs the higher net margin — BIIB at 13.92% versus MRNA at -143.55%.

Which has been the better investment, BIIB or MRNA?

Over the past 5-year, BIIB delivered the higher annualized total return — BIIB at -2.18% versus MRNA at -23.08%. Past performance doesn't predict future results.

Biogen Inc. (BIIB) vs Moderna, Inc. (MRNA)

BIIB leads on 8 of 10 compared metrics.

A side-by-side comparison of Biogen Inc. and Moderna, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of June 16, 2026. The ● marks the stronger figure on each row (cheaper multiple, higher margin/return).

Total return — BIIB vs MRNA

growth of $100 · last 8y

BIIB -38.7%MRNA +186.5%MRNA compounded faster

BIIB MRNA

BIIB vs MRNA: by the numbers

•BIIB is the larger company ($28.83B vs $21.22B market cap).
•BIIB is profitable (13.92% net margin) while MRNA runs a net loss (-143.55%).
•MRNA grew revenue faster over the past five years (-2.60% vs -4.80% CAGR).

Which is better, BIIB or MRNA?

Metric tally: BIIB 8 · MRNA 2

It depends on what you're optimizing for:

GrowthMRNA(faster 5Y revenue CAGR)

QualityBIIB(higher ROIC)

Metrics side by side

Valuation

Metric	BIIB	MRNA
P/E ratio	21.27	—
Forward P/E	12.17	—
P/S ratio	2.99●	9.25
P/B ratio	1.58●	2.78
EV / EBITDA	12.08	—
FCF yield	8.90%	—

Profitability

Metric	BIIB	MRNA
Gross margin	69.77%●	-13.89%
Operating margin	15.65%●	-153.35%
Net margin	13.92%●	-143.55%
ROE	7.36%●	-43.12%
ROIC	6.62%●	-29.70%

Growth (annualized)

Metric	BIIB	MRNA
Revenue CAGR (5Y)	-4.80%	-2.60%●
EPS CAGR (5Y)	-18.67%	—
FCF CAGR (5Y)	-3.59%	126.92%●
Total return CAGR (5Y)	-13.07%●	-23.08%

Frequently asked

Which is better, BIIB or MRNA?: It depends on your goal. growth: MRNA (faster 5Y revenue CAGR); quality: BIIB (higher ROIC). Across all compared metrics, BIIB leads 8 to 2.
Which has grown faster, BIIB or MRNA?: Over the past five years, MRNA grew revenue faster — BIIB at a -4.80% CAGR versus MRNA at -2.60%.
Is BIIB or MRNA more profitable?: BIIB runs the higher net margin — BIIB at 13.92% versus MRNA at -143.55%.
Which has been the better investment, BIIB or MRNA?: Over the past 5-year, BIIB delivered the higher annualized total return — BIIB at -2.18% versus MRNA at -23.08%. Past performance doesn't predict future results.

Go deeper

Full BIIB analysis Full MRNA analysis Interactive comparison tool

Dig into the metrics

Biogen P/E ratio Moderna P/E ratio Biogen dividend yield Moderna dividend yield Biogen ROE Moderna ROE Biogen operating margin Moderna operating margin Biogen revenue growth Moderna revenue growth Biogen free cash flow Moderna free cash flow

Biogen & Moderna appear in these rankings

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Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified June 16, 2026.