Biogen Inc. (BIIB) vs BioNTech SE (BNTX)
BIIB leads on 7 of 10 compared metrics.
A side-by-side comparison of Biogen Inc. and BioNTech SE across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of June 14, 2026. The ● marks the stronger figure on each row (cheaper multiple, higher margin/return).
Total return — BIIB vs BNTX
growth of $100 · last 7yBIIB -10.3%BNTX +535.8%BNTX compounded faster
Log scale — wide-divergence pair
BIIB BNTX
BIIB vs BNTX: by the numbers
- •BIIB is the larger company ($29.53B vs $22.90B market cap).
- •BIIB is profitable (13.92% net margin) while BNTX runs a net loss (-44.73%).
- •BNTX grew revenue faster over the past five years (2.16% vs -4.80% CAGR).
Which is better, BIIB or BNTX?
Metric tally: BIIB 7 · BNTX 3It depends on what you're optimizing for:
GrowthBNTX(faster 5Y revenue CAGR)
QualityBIIB(higher ROIC)
Valuation
| Metric | BIIB | BNTX |
|---|---|---|
| P/E ratio | 21.42 | — |
| Forward P/E | 12.23 | — |
| P/S ratio | 3.01● | 6.97 |
| P/B ratio | 1.59 | 1.06● |
| EV / EBITDA | 12.16 | — |
| FCF yield | 8.83%● | 6.53% |
Profitability
| Metric | BIIB | BNTX |
|---|---|---|
| Gross margin | 69.77% | 73.26%● |
| Operating margin | 15.65%● | -51.55% |
| Net margin | 13.92%● | -44.73% |
| ROE | 7.36%● | -6.79% |
| ROIC | 6.62%● | -3.14% |
Growth (annualized)
| Metric | BIIB | BNTX |
|---|---|---|
| Revenue CAGR (5Y) | -4.80% | 2.16%● |
| EPS CAGR (5Y) | -18.67% | — |
| FCF CAGR (5Y) | -3.59% | — |
| Total return CAGR (5Y) | -12.79%● | -17.39% |
Frequently asked
- Which is better, BIIB or BNTX?
- It depends on your goal. growth: BNTX (faster 5Y revenue CAGR); quality: BIIB (higher ROIC). Across all compared metrics, BIIB leads 7 to 3.
- Which has grown faster, BIIB or BNTX?
- Over the past five years, BNTX grew revenue faster — BIIB at a -4.80% CAGR versus BNTX at 2.16%.
- Is BIIB or BNTX more profitable?
- BIIB runs the higher net margin — BIIB at 13.92% versus BNTX at -44.73%.
- Which has been the better investment, BIIB or BNTX?
- Over the past 5-year, BIIB delivered the higher annualized total return — BIIB at -2.05% versus BNTX at -17.39%. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Biogen P/E ratioBioNTech SE P/E ratioBiogen dividend yieldBioNTech SE dividend yieldBiogen ROEBioNTech SE ROEBiogen operating marginBioNTech SE operating marginBiogen revenue growthBioNTech SE revenue growthBiogen free cash flowBioNTech SE free cash flow
Biogen & BioNTech SE appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified June 14, 2026.