Biofrontera Inc. (BFRI) vs Phio Pharmaceuticals Corp. (PHIO)

A side-by-side comparison of Biofrontera Inc. and Phio Pharmaceuticals Corp. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

Compare
Biofrontera Inc. logo
BFRI
Biofrontera Inc.
$12M
$0.93HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT
Phio Pharmaceuticals Corp. logo
PHIO
Phio Pharmaceuticals Corp.
$12M
$0.99HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT

Total return — BFRI vs PHIO

growth of $100 · dividends reinvested · last 5y
BFRI -99.0% (-60.1%/yr)PHIO -99.4% (-64.6%/yr)BFRI compounded faster over this window
0100200300Start $10020222023202420252026$1$1
BFRI PHIO

BFRI vs PHIO: by the numbers

  • •BFRI is the larger company ($12M vs $12M market cap).
  • •Both run net losses; PHIO's is the smaller (0.00% vs -13.78% net margin).

Metrics side by side

Valuation

MetricBFRIPHIO
P/S ratio0.26N/A
P/B ratio2.000.92

Profitability

MetricBFRIPHIO
Gross margin84.45%0.00%
Operating margin-21.94%0.00%
Net margin-13.78%0.00%
ROE-106.87%-102.40%
ROIC-32.27%-100.51%

Growth (annualized)

MetricBFRIPHIO
Revenue CAGR (5Y)15.55%N/A
Total return CAGR (5Y)N/A-65.73%

Go deeper

Full BFRI analysisFull PHIO analysisInteractive comparison tool

Dig into the metrics

Biofrontera ROEPhio Pharmaceuticals ROEBiofrontera operating marginPhio Pharmaceuticals operating marginBiofrontera revenue growthPhio Pharmaceuticals revenue growthBiofrontera free cash flowPhio Pharmaceuticals free cash flow

Biofrontera & Phio Pharmaceuticals appear in these rankings

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Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.