Beam Therapeutics Inc. (BEAM) vs Shoulder Innovations, Inc. (SI)
A side-by-side comparison of Beam Therapeutics Inc. and Shoulder Innovations, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 2, 2026. Differences are shown without an overall score or investment verdict.
BEAM
Beam Therapeutics Inc.
$24.50HealthcareDelayed quote: Oct 2, 2026, 4:00 PM EDT
SI
Shoulder Innovations, Inc.
$19.01HealthcareDelayed quote: Oct 2, 2026, 4:00 PM EDT
Total return — BEAM vs SI
growth of $100 · dividends reinvested · last 1yBEAM +21.0% (+21.0%/yr)SI +24.6% (+24.6%/yr)SI compounded faster over this window
BEAM SI
BEAM vs SI: by the numbers
- •BEAM is the larger company ($2.52B vs $394M market cap).
- •Both run net losses; BEAM's is the smaller (-54.75% vs -58.33% net margin).
Metrics side by side
Valuation
| Metric | BEAM | SI |
|---|---|---|
| P/S ratio | 16.15 | 6.56 |
| P/B ratio | 2.36 | 3.17 |
Profitability
| Metric | BEAM | SI |
|---|---|---|
| Gross margin | 84.05% | 77.34% |
| Operating margin | -274.57% | -58.53% |
| Net margin | -54.75% | -58.33% |
| ROE | -8.00% | -28.18% |
| ROIC | -28.96% | -25.26% |
Growth (annualized)
| Metric | BEAM | SI |
|---|---|---|
| Revenue CAGR (5Y) | 479.04% | N/A |
| Total return CAGR (5Y) | -22.35% | N/A |
Go deeper
Dig into the metrics
Beam Therapeutics ROEShoulder Innovations ROEBeam Therapeutics operating marginShoulder Innovations operating marginBeam Therapeutics revenue growthShoulder Innovations revenue growthBeam Therapeutics free cash flowShoulder Innovations free cash flow
Beam Therapeutics & Shoulder Innovations appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 2, 2026.