Beam Therapeutics Inc. (BEAM) vs Denali Therapeutics Inc. (DNLI)
A side-by-side comparison of Beam Therapeutics Inc. and Denali Therapeutics Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
BEAM
Beam Therapeutics Inc.
$25.11HealthcareDelayed quote: Oct 6, 2026, 10:45 AM EDT
DNLI
Denali Therapeutics Inc.
$19.12HealthcareDelayed quote: Oct 6, 2026, 10:45 AM EDT
Total return — BEAM vs DNLI
growth of $100 · dividends reinvested · last 7yBEAM +36.9% (+4.6%/yr)DNLI -12.3% (-1.9%/yr)BEAM compounded faster over this window
BEAM DNLI
BEAM vs DNLI: by the numbers
- •DNLI is the larger company ($3.03B vs $2.58B market cap).
- •Both run net losses; BEAM's is the smaller (-54.75% vs -14191.20% net margin).
- •BEAM grew revenue faster over the past five years (479.04% vs 20.68% CAGR).
Metrics side by side
Valuation
| Metric | BEAM | DNLI |
|---|---|---|
| P/S ratio | 16.56 | 841.99 |
| P/B ratio | 2.42 | 3.63 |
Profitability
| Metric | BEAM | DNLI |
|---|---|---|
| Gross margin | 84.05% | 0.00% |
| Operating margin | -274.57% | 0.00% |
| Net margin | -54.75% | -14191.20% |
| ROE | -8.00% | -61.24% |
| ROIC | -28.96% | -50.82% |
Growth (annualized)
| Metric | BEAM | DNLI |
|---|---|---|
| Revenue CAGR (5Y) | 479.04% | 20.68% |
| Total return CAGR (5Y) | -21.41% | -16.91% |
Frequently asked
- Which has grown faster, BEAM or DNLI?
- Over the past five years, BEAM grew revenue faster — BEAM at a 479.04% CAGR versus DNLI at 20.68%.
- How have BEAM and DNLI total returns compared?
- Over the past 5 years, BEAM delivered -21.41% and DNLI delivered -16.91% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Beam Therapeutics ROEDenali Therapeutics ROEBeam Therapeutics operating marginDenali Therapeutics operating marginBeam Therapeutics revenue growthDenali Therapeutics revenue growthBeam Therapeutics free cash flowDenali Therapeutics free cash flow
Beam Therapeutics & Denali Therapeutics appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.