BioCryst Pharmaceuticals, Inc. (BCRX) vs Inspire Medical Systems, Inc. (INSP)
A side-by-side comparison of BioCryst Pharmaceuticals, Inc. and Inspire Medical Systems, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
BCRX
BioCryst Pharmaceuticals, Inc.
$8.10HealthcareDelayed quote: Oct 5, 2026, 4:00 PM EDT
INSP
Inspire Medical Systems, Inc.
$70.75HealthcareDelayed quote: Oct 5, 2026, 4:00 PM EDT
Total return — BCRX vs INSP
growth of $100 · dividends reinvested · last 8yBCRX +60.4% (+6.1%/yr)INSP +183.2% (+13.9%/yr)INSP compounded faster over this window
BCRX INSP
BCRX vs INSP: by the numbers
- •BCRX is the larger company ($2.06B vs $2.05B market cap).
- •INSP is profitable (15.03% net margin) while BCRX runs a net loss (-40.90%).
- •BCRX grew revenue faster over the past five years (64.07% vs 38.69% CAGR).
Metrics side by side
Valuation
| Metric | BCRX | INSP |
|---|---|---|
| P/E ratio | N/A | 15.31 |
| Forward P/E | N/A | 59.24 |
| P/S ratio | 2.19 | 2.28 |
| P/B ratio | N/A | 2.48 |
| EV / EBITDA | N/A | 27.29 |
| FCF yield | 17.35% | 5.72% |
Profitability
| Metric | BCRX | INSP |
|---|---|---|
| Gross margin | 97.82% | 86.13% |
| Operating margin | 38.98% | 6.02% |
| Net margin | -40.90% | 15.03% |
| ROE | N/A | 16.36% |
| ROIC | -89.73% | 6.33% |
Growth (annualized)
| Metric | BCRX | INSP |
|---|---|---|
| Revenue CAGR (5Y) | 64.07% | 38.69% |
| Total return CAGR (5Y) | -10.02% | -21.38% |
Frequently asked
- Which has grown faster, BCRX or INSP?
- Over the past five years, BCRX grew revenue faster — BCRX at a 64.07% CAGR versus INSP at 38.69%.
- Is BCRX or INSP more profitable?
- INSP runs the higher net margin — BCRX at -40.90% versus INSP at 15.03%.
- How have BCRX and INSP total returns compared?
- Over the past 5 years, BCRX delivered -10.02% and INSP delivered -21.38% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Inspire Medical Systems P/E ratioBioCryst Pharmaceuticals ROEInspire Medical Systems ROEBioCryst Pharmaceuticals operating marginInspire Medical Systems operating marginBioCryst Pharmaceuticals revenue growthInspire Medical Systems revenue growthBioCryst Pharmaceuticals free cash flowInspire Medical Systems free cash flow
BioCryst Pharmaceuticals & Inspire Medical Systems appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.