BioCryst Pharmaceuticals, Inc. (BCRX) vs Establishment Labs Holdings Inc. (ESTA)
A side-by-side comparison of BioCryst Pharmaceuticals, Inc. and Establishment Labs Holdings Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
BCRX
BioCryst Pharmaceuticals, Inc.
$8.10HealthcareDelayed quote: Oct 5, 2026, 4:00 PM EDT
ESTA
Establishment Labs Holdings Inc.
$66.47HealthcareDelayed quote: Oct 5, 2026, 4:00 PM EDT
Total return — BCRX vs ESTA
growth of $100 · dividends reinvested · last 8yBCRX +27.4% (+3.1%/yr)ESTA +168.6% (+13.1%/yr)ESTA compounded faster over this window
BCRX ESTA
BCRX vs ESTA: by the numbers
- •BCRX is the larger company ($2.06B vs $1.96B market cap).
- •Both run net losses; ESTA's is the smaller (-15.82% vs -40.90% net margin).
- •BCRX grew revenue faster over the past five years (64.07% vs 17.02% CAGR).
Metrics side by side
Valuation
| Metric | BCRX | ESTA |
|---|---|---|
| P/S ratio | 2.19 | 7.96 |
| P/B ratio | N/A | 90.54 |
| FCF yield | 17.35% | N/A |
Profitability
| Metric | BCRX | ESTA |
|---|---|---|
| Gross margin | 97.82% | 70.49% |
| Operating margin | 38.98% | -18.48% |
| Net margin | -40.90% | -15.82% |
| ROE | N/A | -179.99% |
| ROIC | -89.73% | -6.53% |
Growth (annualized)
| Metric | BCRX | ESTA |
|---|---|---|
| Revenue CAGR (5Y) | 64.07% | 17.02% |
| Total return CAGR (5Y) | -10.02% | -1.56% |
Frequently asked
- Which has grown faster, BCRX or ESTA?
- Over the past five years, BCRX grew revenue faster — BCRX at a 64.07% CAGR versus ESTA at 17.02%.
- How have BCRX and ESTA total returns compared?
- Over the past 5 years, BCRX delivered -10.02% and ESTA delivered -1.56% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
BioCryst Pharmaceuticals ROEEstablishment Labs ROEBioCryst Pharmaceuticals operating marginEstablishment Labs operating marginBioCryst Pharmaceuticals revenue growthEstablishment Labs revenue growthBioCryst Pharmaceuticals free cash flowEstablishment Labs free cash flow
BioCryst Pharmaceuticals & Establishment Labs appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.