BioCryst Pharmaceuticals, Inc. (BCRX) vs Celldex Therapeutics, Inc. (CLDX)
A side-by-side comparison of BioCryst Pharmaceuticals, Inc. and Celldex Therapeutics, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
BCRX
BioCryst Pharmaceuticals, Inc.
$8.00HealthcareDelayed quote: Oct 6, 2026, 1:50 PM EDT
CLDX
Celldex Therapeutics, Inc.
$30.99HealthcareDelayed quote: Oct 6, 2026, 1:50 PM EDT
Total return — BCRX vs CLDX
growth of $100 · dividends reinvested · last 10yBCRX +100.5% (+7.2%/yr)CLDX -36.8% (-4.5%/yr)BCRX compounded faster over this window
BCRX CLDX
BCRX vs CLDX: by the numbers
- •CLDX is the larger company ($2.06B vs $2.03B market cap).
- •Both run net losses; BCRX's is the smaller (-40.90% vs -268385.71% net margin).
- •BCRX grew revenue faster over the past five years (64.07% vs -58.05% CAGR).
Metrics side by side
Valuation
| Metric | BCRX | CLDX |
|---|---|---|
| P/S ratio | 2.16 | 18413.09 |
| P/B ratio | N/A | 2.89 |
| FCF yield | 17.56% | N/A |
Profitability
| Metric | BCRX | CLDX |
|---|---|---|
| Gross margin | 97.82% | 100.00% |
| Operating margin | 38.98% | -19160.00% |
| Net margin | -40.90% | -268385.71% |
| ROE | N/A | -42.07% |
| ROIC | -89.73% | -45.19% |
Growth (annualized)
| Metric | BCRX | CLDX |
|---|---|---|
| Revenue CAGR (5Y) | 64.07% | -58.05% |
| Total return CAGR (5Y) | -10.02% | -10.28% |
Frequently asked
- Which has grown faster, BCRX or CLDX?
- Over the past five years, BCRX grew revenue faster — BCRX at a 64.07% CAGR versus CLDX at -58.05%.
- How have BCRX and CLDX total returns compared?
- Over the past 10 years, BCRX delivered 5.82% and CLDX delivered -6.79% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
BioCryst Pharmaceuticals ROECelldex Therapeutics ROEBioCryst Pharmaceuticals operating marginCelldex Therapeutics operating marginBioCryst Pharmaceuticals revenue growthCelldex Therapeutics revenue growthBioCryst Pharmaceuticals free cash flowCelldex Therapeutics free cash flow
BioCryst Pharmaceuticals & Celldex Therapeutics appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.