AstraZeneca PLC (AZN) vs Thermo Fisher Scientific Inc. (TMO)
A side-by-side comparison of AstraZeneca PLC and Thermo Fisher Scientific Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of September 10, 2026. Differences are shown without an overall score or investment verdict.
AZN
AstraZeneca PLC
$160.17HealthcareDelayed quote: Sep 11, 2026, 4:00 PM EDT
TMO
Thermo Fisher Scientific Inc.
$609.82HealthcareDelayed quote: Sep 11, 2026, 4:00 PM EDT
Total return — AZN vs TMO
growth of $100 · dividends reinvested · last 10yAZN +234.4% (+12.8%/yr)TMO +314.9% (+15.3%/yr)TMO compounded faster over this window
AZN TMO
AZN vs TMO: by the numbers
- •AZN is the larger company ($248.40B vs $226.62B market cap).
- •AZN trades at the lower trailing earnings multiple (24.05 vs 32.80 P/E), one valuation lens rather than an overall verdict.
- •AZN converts more revenue to profit (17.02% vs 15.06% net margin).
- •AZN grew revenue faster over the past five years (15.76% vs 5.00% CAGR).
- •AZN pays the higher dividend yield (2.02% vs 0.30%).
Metrics side by side
Valuation
| Metric | AZN | TMO |
|---|---|---|
| P/E ratio | 24.05 | 32.80 |
| Forward P/E | 15.64 | 24.29 |
| P/S ratio | 4.05 | 4.89 |
| P/B ratio | 4.94 | 4.30 |
| EV / EBITDA | 13.56 | 25.25 |
| FCF yield | 3.52% | 3.23% |
Profitability
| Metric | AZN | TMO |
|---|---|---|
| Gross margin | 81.88% | 40.37% |
| Operating margin | 22.77% | 17.69% |
| Net margin | 17.02% | 15.06% |
| ROE | 20.79% | 13.25% |
| ROIC | 12.83% | 7.44% |
Dividends
| Metric | AZN | TMO |
|---|---|---|
| Dividend yield | 2.02% | 0.30% |
| Payout ratio | 48.50% | 9.68% |
Growth (annualized)
| Metric | AZN | TMO |
|---|---|---|
| Revenue CAGR (5Y) | 15.76% | 5.00% |
| EPS CAGR (5Y) | 22.02% | 1.99% |
| FCF CAGR (5Y) | 14.53% | -1.83% |
| Total return CAGR (5Y) | 9.46% | 1.55% |
Frequently asked
- Which has the lower trailing P/E, AZN or TMO?
- AZN has the lower trailing P/E: AZN trades at 24.05 and TMO at 32.80. P/E is one valuation measure and does not by itself establish which business is cheaper.
- Which has grown faster, AZN or TMO?
- Over the past five years, AZN grew revenue faster — AZN at a 15.76% CAGR versus TMO at 5.00%.
- Does AZN or TMO pay a bigger dividend?
- AZN yields 2.02% and TMO yields 0.30% based on trailing dividends and the latest price.
- Is AZN or TMO more profitable?
- AZN runs the higher net margin — AZN at 17.02% versus TMO at 15.06%.
- How have AZN and TMO total returns compared?
- Over the past 10 years, AZN delivered 12.85% and TMO delivered 15.81% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
AstraZeneca P/E ratioThermo Fisher Scientific P/E ratioAstraZeneca dividend yieldThermo Fisher Scientific dividend yieldAstraZeneca ROEThermo Fisher Scientific ROEAstraZeneca operating marginThermo Fisher Scientific operating marginAstraZeneca revenue growthThermo Fisher Scientific revenue growthAstraZeneca free cash flowThermo Fisher Scientific free cash flow
AstraZeneca & Thermo Fisher Scientific appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified September 10, 2026.