AstraZeneca PLC (AZN) vs Thermo Fisher Scientific Inc. (TMO)

A side-by-side comparison of AstraZeneca PLC and Thermo Fisher Scientific Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of September 10, 2026. Differences are shown without an overall score or investment verdict.

Compare

Total returnAZN vs TMO

growth of $100 · dividends reinvested · last 10y
AZN +234.4% (+12.8%/yr)TMO +314.9% (+15.3%/yr)TMO compounded faster over this window
100200300400Start $10020182020202220242026$334$415
AZN TMO

AZN vs TMO: by the numbers

  • AZN is the larger company ($248.40B vs $226.62B market cap).
  • AZN trades at the lower trailing earnings multiple (24.05 vs 32.80 P/E), one valuation lens rather than an overall verdict.
  • AZN converts more revenue to profit (17.02% vs 15.06% net margin).
  • AZN grew revenue faster over the past five years (15.76% vs 5.00% CAGR).
  • AZN pays the higher dividend yield (2.02% vs 0.30%).

Metrics side by side

Valuation

MetricAZNTMO
P/E ratio24.0532.80
Forward P/E15.6424.29
P/S ratio4.054.89
P/B ratio4.944.30
EV / EBITDA13.5625.25
FCF yield3.52%3.23%

Profitability

MetricAZNTMO
Gross margin81.88%40.37%
Operating margin22.77%17.69%
Net margin17.02%15.06%
ROE20.79%13.25%
ROIC12.83%7.44%

Dividends

MetricAZNTMO
Dividend yield2.02%0.30%
Payout ratio48.50%9.68%

Growth (annualized)

MetricAZNTMO
Revenue CAGR (5Y)15.76%5.00%
EPS CAGR (5Y)22.02%1.99%
FCF CAGR (5Y)14.53%-1.83%
Total return CAGR (5Y)9.46%1.55%

Frequently asked

Which has the lower trailing P/E, AZN or TMO?
AZN has the lower trailing P/E: AZN trades at 24.05 and TMO at 32.80. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, AZN or TMO?
Over the past five years, AZN grew revenue faster — AZN at a 15.76% CAGR versus TMO at 5.00%.
Does AZN or TMO pay a bigger dividend?
AZN yields 2.02% and TMO yields 0.30% based on trailing dividends and the latest price.
Is AZN or TMO more profitable?
AZN runs the higher net margin — AZN at 17.02% versus TMO at 15.06%.
How have AZN and TMO total returns compared?
Over the past 10 years, AZN delivered 12.85% and TMO delivered 15.81% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified September 10, 2026.