AstraZeneca PLC (AZN) vs Thermo Fisher Scientific Inc. (TMO)
AZN leads on 13 of 17 compared metrics, though TMO is the cheaper stock.
A side-by-side comparison of AstraZeneca PLC and Thermo Fisher Scientific Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of June 13, 2026. The ● marks the stronger figure on each row (cheaper multiple, higher margin/return).
AZN
AstraZeneca PLC
$178.75Healthcare
TMO
Thermo Fisher Scientific Inc.
$469.34Healthcare
Total return — AZN vs TMO
growth of $100 · last 30yAZN +723.4%TMO +1154.9%TMO compounded faster
AZN TMO
AZN vs TMO: by the numbers
- •AZN is the larger company ($277.22B vs $174.42B market cap).
- •TMO trades at the lower earnings multiple (25.80 vs 26.92 P/E).
- •AZN converts more revenue to profit (17.19% vs 15.18% net margin).
- •AZN grew revenue faster over the past five years (16.99% vs 6.68% CAGR).
- •AZN pays the higher dividend yield (1.79% vs 0.28%).
Which is better, AZN or TMO?
Metric tally: AZN 13 · TMO 4It depends on what you're optimizing for:
ValueTMO(lower P/E)
GrowthAZN(faster 5Y revenue CAGR)
IncomeAZN(higher dividend yield)
QualityAZN(higher ROIC)
Valuation
| Metric | AZN | TMO |
|---|---|---|
| P/E ratio | 26.92 | 25.80● |
| Forward P/E | 15.33● | 17.26 |
| P/S ratio | 4.62 | 3.87● |
| P/B ratio | 5.90 | 3.37● |
| PEG ratio | 0.14● | 4.51 |
| EV / EBITDA | 14.92● | 19.26 |
| FCF yield | 3.26% | 3.86%● |
Profitability
| Metric | AZN | TMO |
|---|---|---|
| Gross margin | 81.68%● | 39.41% |
| Operating margin | 23.69%● | 17.76% |
| Net margin | 17.19%● | 15.18% |
| ROE | 21.95%● | 13.21% |
| ROIC | 13.03%● | 7.58% |
Dividends
| Metric | AZN | TMO |
|---|---|---|
| Dividend yield | 1.79%● | 0.28% |
| Payout ratio | 48.48% | 7.48% |
Growth (annualized)
| Metric | AZN | TMO |
|---|---|---|
| Revenue CAGR (5Y) | 16.99%● | 6.68% |
| EPS CAGR (5Y) | 22.02%● | 1.99% |
| FCF CAGR (5Y) | 18.52%● | -0.19% |
| Total return CAGR (5Y) | 11.03%● | 0.45% |
Frequently asked
- Which is better, AZN or TMO?
- It depends on your goal. value: TMO (lower P/E); growth: AZN (faster 5Y revenue CAGR); income: AZN (higher dividend yield); quality: AZN (higher ROIC). Across all compared metrics, AZN leads 13 to 4.
- Is AZN or TMO cheaper?
- On trailing earnings, TMO is cheaper: AZN trades at a 26.92 P/E and TMO at 25.80.
- Which has grown faster, AZN or TMO?
- Over the past five years, AZN grew revenue faster — AZN at a 16.99% CAGR versus TMO at 6.68%.
- Does AZN or TMO pay a bigger dividend?
- AZN yields 1.79% and TMO yields 0.28% based on trailing dividends and the latest price.
- Is AZN or TMO more profitable?
- AZN runs the higher net margin — AZN at 17.19% versus TMO at 15.18%.
- Which has been the better investment, AZN or TMO?
- Over the past 10-year, AZN delivered the higher annualized total return — AZN at 15.77% versus TMO at 12.26%. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
AstraZeneca P/E ratioThermo Fisher Scientific P/E ratioAstraZeneca dividend yieldThermo Fisher Scientific dividend yieldAstraZeneca ROEThermo Fisher Scientific ROEAstraZeneca operating marginThermo Fisher Scientific operating marginAstraZeneca revenue growthThermo Fisher Scientific revenue growthAstraZeneca free cash flowThermo Fisher Scientific free cash flow
AstraZeneca & Thermo Fisher Scientific appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified June 13, 2026.