Which has the lower trailing P/E, AZN or PFE?

AZN has the lower trailing P/E: AZN trades at 24.05 and PFE at 36.63. P/E is one valuation measure and does not by itself establish which business is cheaper.

Which has grown faster, AZN or PFE?

Over the past five years, AZN grew revenue faster — AZN at a 15.76% CAGR versus PFE at 6.29%.

Does AZN or PFE pay a bigger dividend?

AZN yields 2.02% and PFE yields 6.19% based on trailing dividends and the latest price.

Is AZN or PFE more profitable?

AZN runs the higher net margin — AZN at 17.02% versus PFE at 6.81%.

How have AZN and PFE total returns compared?

Over the past 10 years, AZN delivered 12.85% and PFE delivered 3.17% annualized total return. Past performance doesn't predict future results.

AstraZeneca PLC (AZN) vs Pfizer Inc. (PFE)

A side-by-side comparison of AstraZeneca PLC and Pfizer Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of September 10, 2026. Differences are shown without an overall score or investment verdict.

AZN

AstraZeneca PLC

$248.40B

$160.17HealthcareDelayed quote: Sep 11, 2026, 4:00 PM EDT

PFE

Pfizer Inc.

$157.99B

$27.72HealthcareDelayed quote: Sep 11, 2026, 4:01 PM EDT

Total return — AZN vs PFE

growth of $100 · dividends reinvested · last 10y

AZN +234.4% (+12.8%/yr)PFE +37.3% (+3.2%/yr)AZN compounded faster over this window

AZN PFE

AZN vs PFE: by the numbers

•AZN is the larger company ($248.40B vs $157.99B market cap).
•AZN trades at the lower trailing earnings multiple (24.05 vs 36.63 P/E), one valuation lens rather than an overall verdict.
•AZN converts more revenue to profit (17.02% vs 6.81% net margin).
•AZN grew revenue faster over the past five years (15.76% vs 6.29% CAGR).
•PFE pays the higher dividend yield (6.19% vs 2.02%).

Metrics side by side

Valuation

Metric	AZN	PFE
P/E ratio	24.05	36.63
Forward P/E	15.64	9.32
P/S ratio	4.05	2.48
P/B ratio	4.94	1.85
EV / EBITDA	13.56	10.15
FCF yield	3.52%	6.95%

Profitability

Metric	AZN	PFE
Gross margin	81.88%	71.32%
Operating margin	22.77%	25.08%
Net margin	17.02%	6.81%
ROE	20.79%	5.09%
ROIC	12.83%	9.33%

Dividends

Metric	AZN	PFE
Dividend yield	2.02%	6.19%
Payout ratio	48.50%	227.27%

Growth (annualized)

Metric	AZN	PFE
Revenue CAGR (5Y)	15.76%	6.29%
EPS CAGR (5Y)	22.02%	-3.78%
FCF CAGR (5Y)	14.53%	-3.11%
Total return CAGR (5Y)	9.46%	-4.68%

Frequently asked

Which has the lower trailing P/E, AZN or PFE?: AZN has the lower trailing P/E: AZN trades at 24.05 and PFE at 36.63. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, AZN or PFE?: Over the past five years, AZN grew revenue faster — AZN at a 15.76% CAGR versus PFE at 6.29%.
Does AZN or PFE pay a bigger dividend?: AZN yields 2.02% and PFE yields 6.19% based on trailing dividends and the latest price.
Is AZN or PFE more profitable?: AZN runs the higher net margin — AZN at 17.02% versus PFE at 6.81%.
How have AZN and PFE total returns compared?: Over the past 10 years, AZN delivered 12.85% and PFE delivered 3.17% annualized total return. Past performance doesn't predict future results.

Go deeper

Full AZN analysis Full PFE analysis Interactive comparison tool

Dig into the metrics

AstraZeneca P/E ratio Pfizer P/E ratio AstraZeneca dividend yield Pfizer dividend yield AstraZeneca ROE Pfizer ROE AstraZeneca operating margin Pfizer operating margin AstraZeneca revenue growth Pfizer revenue growth AstraZeneca free cash flow Pfizer free cash flow

AstraZeneca & Pfizer appear in these rankings

Highest Dividend Yield Stocks Fastest Revenue Growth Stocks Highest FCF Yield Stocks Largest Companies by Market Cap

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified September 10, 2026.