AstraZeneca PLC (AZN) vs Pfizer Inc. (PFE)
AZN leads on 8 of 15 compared metrics, though PFE is the cheaper stock.
A side-by-side comparison of AstraZeneca PLC and Pfizer Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of June 13, 2026. The ● marks the stronger figure on each row (cheaper multiple, higher margin/return).
Total return — AZN vs PFE
growth of $100 · last 30yAZN +723.4%PFE +128.5%AZN compounded faster
AZN PFE
AZN vs PFE: by the numbers
- •AZN is the larger company ($277.22B vs $149.38B market cap).
- •PFE trades at the lower earnings multiple (20.01 vs 26.92 P/E).
- •AZN converts more revenue to profit (17.19% vs 11.83% net margin).
- •AZN grew revenue faster over the past five years (16.99% vs 8.22% CAGR).
- •PFE pays the higher dividend yield (6.56% vs 1.79%).
Which is better, AZN or PFE?
Metric tally: AZN 8 · PFE 7It depends on what you're optimizing for:
ValuePFE(lower P/E)
GrowthAZN(faster 5Y revenue CAGR)
IncomePFE(higher dividend yield)
QualityAZN(higher ROIC)
Valuation
| Metric | AZN | PFE |
|---|---|---|
| P/E ratio | 26.92 | 20.01● |
| Forward P/E | 15.33 | 9.25● |
| P/S ratio | 4.62 | 2.37● |
| P/B ratio | 5.90 | 1.67● |
| PEG ratio | 0.14 | — |
| EV / EBITDA | 14.92 | 12.72● |
| FCF yield | 3.26% | 6.31%● |
Profitability
| Metric | AZN | PFE |
|---|---|---|
| Gross margin | 81.68%● | 69.35% |
| Operating margin | 23.69% | 23.45% |
| Net margin | 17.19%● | 11.83% |
| ROE | 21.95%● | 8.31% |
| ROIC | 13.03%● | 8.84% |
Dividends
| Metric | AZN | PFE |
|---|---|---|
| Dividend yield | 1.79% | 6.56%● |
| Payout ratio | 48.48% | 126.47% |
Growth (annualized)
| Metric | AZN | PFE |
|---|---|---|
| Revenue CAGR (5Y) | 16.99%● | 8.22% |
| EPS CAGR (5Y) | 22.02%● | -3.78% |
| FCF CAGR (5Y) | 18.52%● | -3.79% |
| Total return CAGR (5Y) | 11.03%● | -3.33% |
Frequently asked
- Which is better, AZN or PFE?
- It depends on your goal. value: PFE (lower P/E); growth: AZN (faster 5Y revenue CAGR); income: PFE (higher dividend yield); quality: AZN (higher ROIC). Across all compared metrics, AZN leads 8 to 7.
- Is AZN or PFE cheaper?
- On trailing earnings, PFE is cheaper: AZN trades at a 26.92 P/E and PFE at 20.01.
- Which has grown faster, AZN or PFE?
- Over the past five years, AZN grew revenue faster — AZN at a 16.99% CAGR versus PFE at 8.22%.
- Does AZN or PFE pay a bigger dividend?
- AZN yields 1.79% and PFE yields 6.56% based on trailing dividends and the latest price.
- Is AZN or PFE more profitable?
- AZN runs the higher net margin — AZN at 17.19% versus PFE at 11.83%.
- Which has been the better investment, AZN or PFE?
- Over the past 10-year, AZN delivered the higher annualized total return — AZN at 15.77% versus PFE at 2.13%. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
AstraZeneca P/E ratioPfizer P/E ratioAstraZeneca dividend yieldPfizer dividend yieldAstraZeneca ROEPfizer ROEAstraZeneca operating marginPfizer operating marginAstraZeneca revenue growthPfizer revenue growthAstraZeneca free cash flowPfizer free cash flow
AstraZeneca & Pfizer appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified June 13, 2026.