AstraZeneca PLC (AZN) vs Merck & Co., Inc. (MRK)

AZN leads on 10 of 17 compared metrics.

A side-by-side comparison of AstraZeneca PLC and Merck & Co., Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of June 13, 2026. The ● marks the stronger figure on each row (cheaper multiple, higher margin/return).

Total return — AZN vs MRK

growth of $100 · last 30y
AZN +723.4%MRK +287.9%AZN compounded faster
02004006008001kStart $100200120062011201620212026$823$388
AZN MRK

AZN vs MRK: by the numbers

  • MRK is the larger company ($294.03B vs $277.22B market cap).
  • AZN trades at the lower earnings multiple (26.92 vs 33.54 P/E).
  • AZN converts more revenue to profit (17.19% vs 13.62% net margin).
  • AZN grew revenue faster over the past five years (16.99% vs 8.60% CAGR).
  • MRK pays the higher dividend yield (2.79% vs 1.79%).

Which is better, AZN or MRK?

Metric tally: AZN 10 · MRK 7

It depends on what you're optimizing for:

ValueAZN(lower P/E)
GrowthAZN(faster 5Y revenue CAGR)
IncomeMRK(higher dividend yield)
QualityMRK(higher ROIC)

Valuation

MetricAZNMRK
P/E ratio26.9233.54
Forward P/E15.3312.35
P/S ratio4.624.49
P/B ratio5.906.41
PEG ratio0.141.81
EV / EBITDA14.9219.58
FCF yield3.26%4.80%

Profitability

MetricAZNMRK
Gross margin81.68%75.91%
Operating margin23.69%27.59%
Net margin17.19%13.62%
ROE21.95%19.48%
ROIC13.03%18.27%

Dividends

MetricAZNMRK
Dividend yield1.79%2.79%
Payout ratio48.48%45.48%

Growth (annualized)

MetricAZNMRK
Revenue CAGR (5Y)16.99%8.60%
EPS CAGR (5Y)22.02%21.21%
FCF CAGR (5Y)18.52%15.69%
Total return CAGR (5Y)11.03%12.79%

Frequently asked

Which is better, AZN or MRK?
It depends on your goal. value: AZN (lower P/E); growth: AZN (faster 5Y revenue CAGR); income: MRK (higher dividend yield); quality: MRK (higher ROIC). Across all compared metrics, AZN leads 10 to 7.
Is AZN or MRK cheaper?
On trailing earnings, AZN is cheaper: AZN trades at a 26.92 P/E and MRK at 33.54.
Which has grown faster, AZN or MRK?
Over the past five years, AZN grew revenue faster — AZN at a 16.99% CAGR versus MRK at 8.60%.
Does AZN or MRK pay a bigger dividend?
AZN yields 1.79% and MRK yields 2.79% based on trailing dividends and the latest price.
Is AZN or MRK more profitable?
AZN runs the higher net margin — AZN at 17.19% versus MRK at 13.62%.
Which has been the better investment, AZN or MRK?
Over the past 10-year, AZN delivered the higher annualized total return — AZN at 15.77% versus MRK at 11.57%. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified June 13, 2026.