AstraZeneca PLC (AZN) vs Merck & Co., Inc. (MRK)
AZN leads on 10 of 17 compared metrics.
A side-by-side comparison of AstraZeneca PLC and Merck & Co., Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of June 13, 2026. The ● marks the stronger figure on each row (cheaper multiple, higher margin/return).
Total return — AZN vs MRK
growth of $100 · last 30yAZN +723.4%MRK +287.9%AZN compounded faster
AZN MRK
AZN vs MRK: by the numbers
- •MRK is the larger company ($294.03B vs $277.22B market cap).
- •AZN trades at the lower earnings multiple (26.92 vs 33.54 P/E).
- •AZN converts more revenue to profit (17.19% vs 13.62% net margin).
- •AZN grew revenue faster over the past five years (16.99% vs 8.60% CAGR).
- •MRK pays the higher dividend yield (2.79% vs 1.79%).
Which is better, AZN or MRK?
Metric tally: AZN 10 · MRK 7It depends on what you're optimizing for:
ValueAZN(lower P/E)
GrowthAZN(faster 5Y revenue CAGR)
IncomeMRK(higher dividend yield)
QualityMRK(higher ROIC)
Valuation
| Metric | AZN | MRK |
|---|---|---|
| P/E ratio | 26.92● | 33.54 |
| Forward P/E | 15.33 | 12.35● |
| P/S ratio | 4.62 | 4.49● |
| P/B ratio | 5.90● | 6.41 |
| PEG ratio | 0.14● | 1.81 |
| EV / EBITDA | 14.92● | 19.58 |
| FCF yield | 3.26% | 4.80%● |
Profitability
| Metric | AZN | MRK |
|---|---|---|
| Gross margin | 81.68%● | 75.91% |
| Operating margin | 23.69% | 27.59%● |
| Net margin | 17.19%● | 13.62% |
| ROE | 21.95%● | 19.48% |
| ROIC | 13.03% | 18.27%● |
Dividends
| Metric | AZN | MRK |
|---|---|---|
| Dividend yield | 1.79% | 2.79%● |
| Payout ratio | 48.48% | 45.48% |
Growth (annualized)
| Metric | AZN | MRK |
|---|---|---|
| Revenue CAGR (5Y) | 16.99%● | 8.60% |
| EPS CAGR (5Y) | 22.02%● | 21.21% |
| FCF CAGR (5Y) | 18.52%● | 15.69% |
| Total return CAGR (5Y) | 11.03% | 12.79%● |
Frequently asked
- Which is better, AZN or MRK?
- It depends on your goal. value: AZN (lower P/E); growth: AZN (faster 5Y revenue CAGR); income: MRK (higher dividend yield); quality: MRK (higher ROIC). Across all compared metrics, AZN leads 10 to 7.
- Is AZN or MRK cheaper?
- On trailing earnings, AZN is cheaper: AZN trades at a 26.92 P/E and MRK at 33.54.
- Which has grown faster, AZN or MRK?
- Over the past five years, AZN grew revenue faster — AZN at a 16.99% CAGR versus MRK at 8.60%.
- Does AZN or MRK pay a bigger dividend?
- AZN yields 1.79% and MRK yields 2.79% based on trailing dividends and the latest price.
- Is AZN or MRK more profitable?
- AZN runs the higher net margin — AZN at 17.19% versus MRK at 13.62%.
- Which has been the better investment, AZN or MRK?
- Over the past 10-year, AZN delivered the higher annualized total return — AZN at 15.77% versus MRK at 11.57%. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
AstraZeneca P/E ratioMerck & P/E ratioAstraZeneca dividend yieldMerck & dividend yieldAstraZeneca ROEMerck & ROEAstraZeneca operating marginMerck & operating marginAstraZeneca revenue growthMerck & revenue growthAstraZeneca free cash flowMerck & free cash flow
AstraZeneca & Merck & appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified June 13, 2026.