AstraZeneca PLC (AZN) vs Eli Lilly and Company (LLY)

LLY leads on 9 of 17 compared metrics, though AZN is the cheaper stock.

A side-by-side comparison of AstraZeneca PLC and Eli Lilly and Company across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of June 13, 2026. The ● marks the stronger figure on each row (cheaper multiple, higher margin/return).

Total return — AZN vs LLY

growth of $100 · last 30y
AZN +723.4%LLY +3454.0%LLY compounded faster
01k2k3kStart $100200120062011201620212026$823$3,554
AZN LLY

AZN vs LLY: by the numbers

  • LLY is the larger company ($1.07T vs $277.22B market cap).
  • AZN trades at the lower earnings multiple (26.92 vs 40.25 P/E).
  • LLY converts more revenue to profit (34.98% vs 17.19% net margin).
  • LLY grew revenue faster over the past five years (23.17% vs 16.99% CAGR).
  • AZN pays the higher dividend yield (1.79% vs 0.57%).

Which is better, AZN or LLY?

Metric tally: AZN 8 · LLY 9

It depends on what you're optimizing for:

ValueAZN(lower P/E)
GrowthLLY(faster 5Y revenue CAGR)
IncomeAZN(higher dividend yield)
QualityLLY(higher ROIC)

Valuation

MetricAZNLLY
P/E ratio26.9240.25
Forward P/E15.3325.41
P/S ratio4.6214.05
P/B ratio5.9032.54
PEG ratio0.140.49
EV / EBITDA14.9231.47
FCF yield3.26%1.34%

Profitability

MetricAZNLLY
Gross margin81.68%83.51%
Operating margin23.69%45.87%
Net margin17.19%34.98%
ROE21.95%81.01%
ROIC13.03%30.20%

Dividends

MetricAZNLLY
Dividend yield1.79%0.57%
Payout ratio48.48%28.09%

Growth (annualized)

MetricAZNLLY
Revenue CAGR (5Y)16.99%23.17%
EPS CAGR (5Y)22.02%28.88%
FCF CAGR (5Y)18.52%19.54%
Total return CAGR (5Y)11.03%39.57%

Frequently asked

Which is better, AZN or LLY?
It depends on your goal. value: AZN (lower P/E); growth: LLY (faster 5Y revenue CAGR); income: AZN (higher dividend yield); quality: LLY (higher ROIC). Across all compared metrics, LLY leads 9 to 8.
Is AZN or LLY cheaper?
On trailing earnings, AZN is cheaper: AZN trades at a 26.92 P/E and LLY at 40.25.
Which has grown faster, AZN or LLY?
Over the past five years, LLY grew revenue faster — AZN at a 16.99% CAGR versus LLY at 23.17%.
Does AZN or LLY pay a bigger dividend?
AZN yields 1.79% and LLY yields 0.57% based on trailing dividends and the latest price.
Is AZN or LLY more profitable?
LLY runs the higher net margin — AZN at 17.19% versus LLY at 34.98%.
Which has been the better investment, AZN or LLY?
Over the past 10-year, LLY delivered the higher annualized total return — AZN at 15.77% versus LLY at 33.50%. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified June 13, 2026.