AstraZeneca PLC (AZN) vs Eli Lilly and Company (LLY)

A side-by-side comparison of AstraZeneca PLC and Eli Lilly and Company across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of September 10, 2026. Differences are shown without an overall score or investment verdict.

Compare

Total returnAZN vs LLY

growth of $100 · dividends reinvested · last 10y
AZN +228.1% (+12.6%/yr)LLY +1566.6% (+32.5%/yr)LLY compounded faster over this window
Log scale — wide-divergence pair
101001k10kStart $10020182020202220242026$328$1,667
AZN LLY

AZN vs LLY: by the numbers

  • LLY is the larger company ($1.05T vs $248.40B market cap).
  • AZN trades at the lower trailing earnings multiple (24.05 vs 37.42 P/E), one valuation lens rather than an overall verdict.
  • LLY converts more revenue to profit (33.53% vs 17.02% net margin).
  • LLY grew revenue faster over the past five years (24.42% vs 15.76% CAGR).
  • AZN pays the higher dividend yield (2.02% vs 0.60%).

Metrics side by side

Valuation

MetricAZNLLY
P/E ratio24.0537.42
Forward P/E15.6430.64
P/S ratio4.0513.18
P/B ratio4.9431.00
EV / EBITDA13.5629.91
FCF yield3.52%1.91%

Profitability

MetricAZNLLY
Gross margin81.88%84.01%
Operating margin22.77%43.92%
Net margin17.02%33.53%
ROE20.79%78.84%
ROIC12.83%27.38%

Dividends

MetricAZNLLY
Dividend yield2.02%0.60%
Payout ratio48.50%22.45%

Growth (annualized)

MetricAZNLLY
Revenue CAGR (5Y)15.76%24.42%
EPS CAGR (5Y)22.02%28.88%
FCF CAGR (5Y)14.53%32.91%
Total return CAGR (5Y)9.46%37.46%

Frequently asked

Which has the lower trailing P/E, AZN or LLY?
AZN has the lower trailing P/E: AZN trades at 24.05 and LLY at 37.42. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, AZN or LLY?
Over the past five years, LLY grew revenue faster — AZN at a 15.76% CAGR versus LLY at 24.42%.
Does AZN or LLY pay a bigger dividend?
AZN yields 2.02% and LLY yields 0.60% based on trailing dividends and the latest price.
Is AZN or LLY more profitable?
LLY runs the higher net margin — AZN at 17.02% versus LLY at 33.53%.
How have AZN and LLY total returns compared?
Over the past 10 years, AZN delivered 12.85% and LLY delivered 32.58% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified September 10, 2026.