AstraZeneca PLC (AZN) vs Eli Lilly and Company (LLY)
A side-by-side comparison of AstraZeneca PLC and Eli Lilly and Company across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of September 10, 2026. Differences are shown without an overall score or investment verdict.
AZN
AstraZeneca PLC
$160.17HealthcareDelayed quote: Sep 11, 2026, 4:00 PM EDT
LLY
Eli Lilly and Company
$1,115.25HealthcareDelayed quote: Sep 11, 2026, 3:59 PM EDT
Total return — AZN vs LLY
growth of $100 · dividends reinvested · last 10yAZN +228.1% (+12.6%/yr)LLY +1566.6% (+32.5%/yr)LLY compounded faster over this window
Log scale — wide-divergence pair
AZN LLY
AZN vs LLY: by the numbers
- •LLY is the larger company ($1.05T vs $248.40B market cap).
- •AZN trades at the lower trailing earnings multiple (24.05 vs 37.42 P/E), one valuation lens rather than an overall verdict.
- •LLY converts more revenue to profit (33.53% vs 17.02% net margin).
- •LLY grew revenue faster over the past five years (24.42% vs 15.76% CAGR).
- •AZN pays the higher dividend yield (2.02% vs 0.60%).
Metrics side by side
Valuation
| Metric | AZN | LLY |
|---|---|---|
| P/E ratio | 24.05 | 37.42 |
| Forward P/E | 15.64 | 30.64 |
| P/S ratio | 4.05 | 13.18 |
| P/B ratio | 4.94 | 31.00 |
| EV / EBITDA | 13.56 | 29.91 |
| FCF yield | 3.52% | 1.91% |
Profitability
| Metric | AZN | LLY |
|---|---|---|
| Gross margin | 81.88% | 84.01% |
| Operating margin | 22.77% | 43.92% |
| Net margin | 17.02% | 33.53% |
| ROE | 20.79% | 78.84% |
| ROIC | 12.83% | 27.38% |
Dividends
| Metric | AZN | LLY |
|---|---|---|
| Dividend yield | 2.02% | 0.60% |
| Payout ratio | 48.50% | 22.45% |
Growth (annualized)
| Metric | AZN | LLY |
|---|---|---|
| Revenue CAGR (5Y) | 15.76% | 24.42% |
| EPS CAGR (5Y) | 22.02% | 28.88% |
| FCF CAGR (5Y) | 14.53% | 32.91% |
| Total return CAGR (5Y) | 9.46% | 37.46% |
Frequently asked
- Which has the lower trailing P/E, AZN or LLY?
- AZN has the lower trailing P/E: AZN trades at 24.05 and LLY at 37.42. P/E is one valuation measure and does not by itself establish which business is cheaper.
- Which has grown faster, AZN or LLY?
- Over the past five years, LLY grew revenue faster — AZN at a 15.76% CAGR versus LLY at 24.42%.
- Does AZN or LLY pay a bigger dividend?
- AZN yields 2.02% and LLY yields 0.60% based on trailing dividends and the latest price.
- Is AZN or LLY more profitable?
- LLY runs the higher net margin — AZN at 17.02% versus LLY at 33.53%.
- How have AZN and LLY total returns compared?
- Over the past 10 years, AZN delivered 12.85% and LLY delivered 32.58% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
AstraZeneca P/E ratioEli Lilly P/E ratioAstraZeneca dividend yieldEli Lilly dividend yieldAstraZeneca ROEEli Lilly ROEAstraZeneca operating marginEli Lilly operating marginAstraZeneca revenue growthEli Lilly revenue growthAstraZeneca free cash flowEli Lilly free cash flow
AstraZeneca & Eli Lilly appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified September 10, 2026.