AstraZeneca PLC (AZN) vs Gilead Sciences, Inc. (GILD)

A side-by-side comparison of AstraZeneca PLC and Gilead Sciences, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of September 10, 2026. Differences are shown without an overall score or investment verdict.

Compare

Total returnAZN vs GILD

growth of $100 · dividends reinvested · last 10y
AZN +217.1% (+12.2%/yr)GILD +161.3% (+10.1%/yr)AZN compounded faster over this window
100200300400Start $10020182020202220242026$317$261
AZN GILD

AZN vs GILD: by the numbers

  • AZN is the larger company ($248.40B vs $178.44B market cap).
  • AZN is profitable (17.02% net margin) while GILD runs a net loss (-10.64%).
  • AZN grew revenue faster over the past five years (15.76% vs 2.72% CAGR).
  • GILD pays the higher dividend yield (2.22% vs 2.02%).

Metrics side by side

Valuation

MetricAZNGILD
P/E ratio24.05N/A
Forward P/E15.64N/A
P/S ratio4.055.86
P/B ratio4.9415.09
EV / EBITDA13.56N/A
FCF yield3.52%7.27%

Profitability

MetricAZNGILD
Gross margin81.88%79.59%
Operating margin22.77%39.74%
Net margin17.02%-10.64%
ROE20.79%-27.39%
ROIC12.83%-3.66%

Dividends

MetricAZNGILD
Dividend yield2.02%2.22%
Payout ratio48.50%N/A

Growth (annualized)

MetricAZNGILD
Revenue CAGR (5Y)15.76%2.72%
EPS CAGR (5Y)22.02%133.83%
FCF CAGR (5Y)14.53%9.27%
Total return CAGR (5Y)9.46%19.60%

Frequently asked

Which has grown faster, AZN or GILD?
Over the past five years, AZN grew revenue faster — AZN at a 15.76% CAGR versus GILD at 2.72%.
Does AZN or GILD pay a bigger dividend?
AZN yields 2.02% and GILD yields 2.22% based on trailing dividends and the latest price.
Is AZN or GILD more profitable?
AZN runs the higher net margin — AZN at 17.02% versus GILD at -10.64%.
How have AZN and GILD total returns compared?
Over the past 10 years, AZN delivered 12.85% and GILD delivered 10.21% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified September 10, 2026.