AstraZeneca PLC (AZN) vs Gilead Sciences, Inc. (GILD)
A side-by-side comparison of AstraZeneca PLC and Gilead Sciences, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of September 10, 2026. Differences are shown without an overall score or investment verdict.
AZN
AstraZeneca PLC
$160.17HealthcareDelayed quote: Sep 11, 2026, 4:00 PM EDT
GILD
Gilead Sciences, Inc.
$143.72HealthcareDelayed quote: Sep 11, 2026, 4:00 PM EDT
Total return — AZN vs GILD
growth of $100 · dividends reinvested · last 10yAZN +217.1% (+12.2%/yr)GILD +161.3% (+10.1%/yr)AZN compounded faster over this window
AZN GILD
AZN vs GILD: by the numbers
- •AZN is the larger company ($248.40B vs $178.44B market cap).
- •AZN is profitable (17.02% net margin) while GILD runs a net loss (-10.64%).
- •AZN grew revenue faster over the past five years (15.76% vs 2.72% CAGR).
- •GILD pays the higher dividend yield (2.22% vs 2.02%).
Metrics side by side
Valuation
| Metric | AZN | GILD |
|---|---|---|
| P/E ratio | 24.05 | N/A |
| Forward P/E | 15.64 | N/A |
| P/S ratio | 4.05 | 5.86 |
| P/B ratio | 4.94 | 15.09 |
| EV / EBITDA | 13.56 | N/A |
| FCF yield | 3.52% | 7.27% |
Profitability
| Metric | AZN | GILD |
|---|---|---|
| Gross margin | 81.88% | 79.59% |
| Operating margin | 22.77% | 39.74% |
| Net margin | 17.02% | -10.64% |
| ROE | 20.79% | -27.39% |
| ROIC | 12.83% | -3.66% |
Dividends
| Metric | AZN | GILD |
|---|---|---|
| Dividend yield | 2.02% | 2.22% |
| Payout ratio | 48.50% | N/A |
Growth (annualized)
| Metric | AZN | GILD |
|---|---|---|
| Revenue CAGR (5Y) | 15.76% | 2.72% |
| EPS CAGR (5Y) | 22.02% | 133.83% |
| FCF CAGR (5Y) | 14.53% | 9.27% |
| Total return CAGR (5Y) | 9.46% | 19.60% |
Frequently asked
- Which has grown faster, AZN or GILD?
- Over the past five years, AZN grew revenue faster — AZN at a 15.76% CAGR versus GILD at 2.72%.
- Does AZN or GILD pay a bigger dividend?
- AZN yields 2.02% and GILD yields 2.22% based on trailing dividends and the latest price.
- Is AZN or GILD more profitable?
- AZN runs the higher net margin — AZN at 17.02% versus GILD at -10.64%.
- How have AZN and GILD total returns compared?
- Over the past 10 years, AZN delivered 12.85% and GILD delivered 10.21% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
AstraZeneca P/E ratioAstraZeneca dividend yieldGilead Sciences dividend yieldAstraZeneca ROEGilead Sciences ROEAstraZeneca operating marginGilead Sciences operating marginAstraZeneca revenue growthGilead Sciences revenue growthAstraZeneca free cash flowGilead Sciences free cash flow
AstraZeneca & Gilead Sciences appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified September 10, 2026.