How have AYTU and NXTC total returns compared?

Over the past 5 years, AYTU delivered -48.14% and NXTC delivered -44.29% annualized total return. Past performance doesn't predict future results.

Aytu BioPharma, Inc. (AYTU) vs NextCure, Inc. (NXTC)

A side-by-side comparison of Aytu BioPharma, Inc. and NextCure, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

AYTU

Aytu BioPharma, Inc.

$23M

$2.11HealthcareDelayed quote: Oct 6, 2026, 11:38 AM EDT

NXTC

NextCure, Inc.

$19M

$5.33HealthcareDelayed quote: Oct 6, 2026, 12:10 PM EDT

Total return — AYTU vs NXTC

growth of $100 · dividends reinvested · last 7y

AYTU -99.6% (-53.9%/yr)NXTC -97.9% (-42.4%/yr)NXTC compounded faster over this window

AYTU NXTC

AYTU vs NXTC: by the numbers

•AYTU is the larger company ($23M vs $19M market cap).
•Both run net losses; NXTC's is the smaller (0.00% vs -24.76% net margin).

Metrics side by side

Valuation

Metric	AYTU	NXTC
P/S ratio	0.39	N/A
P/B ratio	0.64	1.58
FCF yield	14.36%	N/A

Profitability

Metric	AYTU	NXTC
Gross margin	63.95%	0.00%
Operating margin	-14.44%	0.00%
Net margin	-24.76%	0.00%
ROE	-40.40%	-351.86%
ROIC	-14.21%	-259.91%

Growth (annualized)

Metric	AYTU	NXTC
Revenue CAGR (5Y)	-2.59%	N/A
Total return CAGR (5Y)	-48.14%	-44.29%

Frequently asked

How have AYTU and NXTC total returns compared?: Over the past 5 years, AYTU delivered -48.14% and NXTC delivered -44.29% annualized total return. Past performance doesn't predict future results.

Go deeper

Full AYTU analysis Full NXTC analysis Interactive comparison tool

Dig into the metrics

Aytu BioPharma ROE NextCure ROE Aytu BioPharma operating margin NextCure operating margin Aytu BioPharma revenue growth NextCure revenue growth Aytu BioPharma free cash flow NextCure free cash flow

Aytu BioPharma & NextCure appear in these rankings

Highest FCF Yield Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.