American Express Company (AXP) vs AstraZeneca PLC (AZN)
AXP and AZN are evenly matched — 7 metrics each of 14.
A side-by-side comparison of American Express Company and AstraZeneca PLC across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of June 15, 2026. The ● marks the stronger figure on each row (cheaper multiple, higher margin/return).
AXP
American Express Company
$325.44Financial Services
AZN
AstraZeneca PLC
$178.75Healthcare
Total return — AXP vs AZN
growth of $100 · last 30yAXP +2361.7%AZN +732.9%AXP compounded faster
AXP AZN
AXP vs AZN: by the numbers
- •AZN is the larger company ($277.22B vs $222.06B market cap).
- •AXP trades at the lower earnings multiple (20.30 vs 26.92 P/E).
- •AZN converts more revenue to profit (17.19% vs 13.61% net margin).
- •AXP grew revenue faster over the past five years (17.35% vs 16.99% CAGR).
- •AZN pays the higher dividend yield (1.79% vs 1.05%).
Which is better, AXP or AZN?
Metric tally: AXP 7 · AZN 7It depends on what you're optimizing for:
ValueAXP(lower P/E)
GrowthAXP(faster 5Y revenue CAGR)
IncomeAZN(higher dividend yield)
QualityAZN(higher ROIC)
Metrics side by side
Valuation
| Metric | AXP | AZN |
|---|---|---|
| P/E ratio | 20.30● | 26.92 |
| Forward P/E | 16.15 | 15.33● |
| P/S ratio | 2.71● | 4.62 |
| P/B ratio | 6.57 | 5.90● |
| PEG ratio | 2.43 | 0.14● |
| EV / EBITDA | — | 14.92 |
| FCF yield | — | 2.89% |
Profitability
| Metric | AXP | AZN |
|---|---|---|
| Gross margin | 83.50%● | 81.68% |
| Operating margin | 20.70% | 23.69%● |
| Net margin | 13.61% | 17.19%● |
| ROE | 33.00%● | 21.95% |
| ROIC | 8.29% | 13.03%● |
Dividends
| Metric | AXP | AZN |
|---|---|---|
| Dividend yield | 1.05% | 1.79%● |
| Payout ratio | 22.13% | 48.48% |
Growth (annualized)
| Metric | AXP | AZN |
|---|---|---|
| Revenue CAGR (5Y) | 17.35%● | 16.99% |
| EPS CAGR (5Y) | 32.53%● | 22.02% |
| FCF CAGR (5Y) | — | 15.68% |
| Total return CAGR (5Y) | 16.01%● | 11.03% |
Frequently asked
- Which is better, AXP or AZN?
- It depends on your goal. value: AXP (lower P/E); growth: AXP (faster 5Y revenue CAGR); income: AZN (higher dividend yield); quality: AZN (higher ROIC). Across all compared metrics, they are evenly matched.
- Is AXP or AZN cheaper?
- On trailing earnings, AXP is cheaper: AXP trades at a 20.30 P/E and AZN at 26.92.
- Which has grown faster, AXP or AZN?
- Over the past five years, AXP grew revenue faster — AXP at a 17.35% CAGR versus AZN at 16.99%.
- Does AXP or AZN pay a bigger dividend?
- AXP yields 1.05% and AZN yields 1.79% based on trailing dividends and the latest price.
- Is AXP or AZN more profitable?
- AZN runs the higher net margin — AXP at 13.61% versus AZN at 17.19%.
- Which has been the better investment, AXP or AZN?
- Over the past 10-year, AXP delivered the higher annualized total return — AXP at 19.13% versus AZN at 15.77%. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
American Express P/E ratioAstraZeneca P/E ratioAmerican Express dividend yieldAstraZeneca dividend yieldAmerican Express ROEAstraZeneca ROEAmerican Express operating marginAstraZeneca operating marginAmerican Express revenue growthAstraZeneca revenue growthAmerican Express free cash flowAstraZeneca free cash flow
American Express & AstraZeneca appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified June 15, 2026.