Which has grown faster, AXGN or INSP?

Over the past five years, INSP grew revenue faster — AXGN at a 13.99% CAGR versus INSP at 38.69%.

Is AXGN or INSP more profitable?

INSP runs the higher net margin — AXGN at -13.36% versus INSP at 15.03%.

How have AXGN and INSP total returns compared?

Over the past 5 years, AXGN delivered 19.40% and INSP delivered -21.38% annualized total return. Past performance doesn't predict future results.

AxoGen, Inc. (AXGN) vs Inspire Medical Systems, Inc. (INSP)

A side-by-side comparison of AxoGen, Inc. and Inspire Medical Systems, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

AXGN

AxoGen, Inc.

$2.00B

$37.22HealthcareDelayed quote: Oct 5, 2026, 4:00 PM EDT

INSP

Inspire Medical Systems, Inc.

$2.05B

$70.75HealthcareDelayed quote: Oct 5, 2026, 4:00 PM EDT

Total return — AXGN vs INSP

growth of $100 · dividends reinvested · last 8y

AXGN -6.8% (-0.9%/yr)INSP +183.2% (+13.9%/yr)INSP compounded faster over this window

AXGN INSP

AXGN vs INSP: by the numbers

•INSP is the larger company ($2.05B vs $2.00B market cap).
•INSP is profitable (15.03% net margin) while AXGN runs a net loss (-13.36%).
•INSP grew revenue faster over the past five years (38.69% vs 13.99% CAGR).

Metrics side by side

Valuation

Metric	AXGN	INSP
P/E ratio	N/A	15.31
Forward P/E	84.11	59.24
P/S ratio	7.97	2.28
P/B ratio	7.81	2.48
EV / EBITDA	N/A	27.29
FCF yield	0.13%	5.72%

Profitability

Metric	AXGN	INSP
Gross margin	74.56%	86.13%
Operating margin	-5.12%	6.02%
Net margin	-13.36%	15.03%
ROE	-13.09%	16.36%
ROIC	-4.68%	6.33%

Growth (annualized)

Metric	AXGN	INSP
Revenue CAGR (5Y)	13.99%	38.69%
Total return CAGR (5Y)	19.40%	-21.38%

Frequently asked

Which has grown faster, AXGN or INSP?: Over the past five years, INSP grew revenue faster — AXGN at a 13.99% CAGR versus INSP at 38.69%.
Is AXGN or INSP more profitable?: INSP runs the higher net margin — AXGN at -13.36% versus INSP at 15.03%.
How have AXGN and INSP total returns compared?: Over the past 5 years, AXGN delivered 19.40% and INSP delivered -21.38% annualized total return. Past performance doesn't predict future results.

Go deeper

Full AXGN analysis Full INSP analysis Interactive comparison tool

Dig into the metrics

Inspire Medical Systems P/E ratio AxoGen ROE Inspire Medical Systems ROE AxoGen operating margin Inspire Medical Systems operating margin AxoGen revenue growth Inspire Medical Systems revenue growth AxoGen free cash flow Inspire Medical Systems free cash flow

AxoGen & Inspire Medical Systems appear in these rankings

Fastest Revenue Growth Stocks Highest FCF Yield Stocks Highest 10-Year Total Return Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.