AxoGen, Inc. (AXGN) vs Establishment Labs Holdings Inc. (ESTA)
A side-by-side comparison of AxoGen, Inc. and Establishment Labs Holdings Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
AXGN
AxoGen, Inc.
$37.22HealthcareDelayed quote: Oct 5, 2026, 4:00 PM EDT
ESTA
Establishment Labs Holdings Inc.
$66.47HealthcareDelayed quote: Oct 5, 2026, 4:00 PM EDT
Total return — AXGN vs ESTA
growth of $100 · dividends reinvested · last 8yAXGN -32.2% (-4.7%/yr)ESTA +168.6% (+13.1%/yr)ESTA compounded faster over this window
AXGN ESTA
AXGN vs ESTA: by the numbers
- •AXGN is the larger company ($2.00B vs $1.96B market cap).
- •Both run net losses; AXGN's is the smaller (-13.36% vs -15.82% net margin).
- •ESTA grew revenue faster over the past five years (17.02% vs 13.99% CAGR).
Metrics side by side
Valuation
| Metric | AXGN | ESTA |
|---|---|---|
| Forward P/E | 84.11 | N/A |
| P/S ratio | 7.97 | 7.96 |
| P/B ratio | 7.81 | 90.54 |
| FCF yield | 0.13% | N/A |
Profitability
| Metric | AXGN | ESTA |
|---|---|---|
| Gross margin | 74.56% | 70.49% |
| Operating margin | -5.12% | -18.48% |
| Net margin | -13.36% | -15.82% |
| ROE | -13.09% | -179.99% |
| ROIC | -4.68% | -6.53% |
Growth (annualized)
| Metric | AXGN | ESTA |
|---|---|---|
| Revenue CAGR (5Y) | 13.99% | 17.02% |
| Total return CAGR (5Y) | 19.40% | -1.56% |
Frequently asked
- Which has grown faster, AXGN or ESTA?
- Over the past five years, ESTA grew revenue faster — AXGN at a 13.99% CAGR versus ESTA at 17.02%.
- How have AXGN and ESTA total returns compared?
- Over the past 5 years, AXGN delivered 19.40% and ESTA delivered -1.56% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
AxoGen ROEEstablishment Labs ROEAxoGen operating marginEstablishment Labs operating marginAxoGen revenue growthEstablishment Labs revenue growthAxoGen free cash flowEstablishment Labs free cash flow
AxoGen & Establishment Labs appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.