Which has the lower trailing P/E, AUPH or INSP?

AUPH has the lower trailing P/E: AUPH trades at 6.86 and INSP at 15.31. P/E is one valuation measure and does not by itself establish which business is cheaper.

Which has grown faster, AUPH or INSP?

Over the past five years, AUPH grew revenue faster — AUPH at a 40.17% CAGR versus INSP at 38.69%.

Is AUPH or INSP more profitable?

AUPH runs the higher net margin — AUPH at 100.84% versus INSP at 15.03%.

How have AUPH and INSP total returns compared?

Over the past 5 years, AUPH delivered -5.88% and INSP delivered -21.38% annualized total return. Past performance doesn't predict future results.

Aurinia Pharmaceuticals Inc. (AUPH) vs Inspire Medical Systems, Inc. (INSP)

A side-by-side comparison of Aurinia Pharmaceuticals Inc. and Inspire Medical Systems, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

AUPH

Aurinia Pharmaceuticals Inc.

$2.02B

$15.72HealthcareDelayed quote: Oct 5, 2026, 4:00 PM EDT

INSP

Inspire Medical Systems, Inc.

$2.05B

$70.75HealthcareDelayed quote: Oct 5, 2026, 4:00 PM EDT

Total return — AUPH vs INSP

growth of $100 · dividends reinvested · last 8y

AUPH +202.9% (+14.9%/yr)INSP +183.2% (+13.9%/yr)AUPH compounded faster over this window

AUPH INSP

AUPH vs INSP: by the numbers

•INSP is the larger company ($2.05B vs $2.02B market cap).
•AUPH trades at the lower trailing earnings multiple (6.86 vs 15.31 P/E), one valuation lens rather than an overall verdict.
•AUPH converts more revenue to profit (100.84% vs 15.03% net margin).
•AUPH grew revenue faster over the past five years (40.17% vs 38.69% CAGR).

Metrics side by side

Valuation

Metric	AUPH	INSP
P/E ratio	6.86	15.31
Forward P/E	16.65	59.24
P/S ratio	6.49	2.28
P/B ratio	3.29	2.48
EV / EBITDA	11.18	27.29
FCF yield	8.59%	5.72%

Profitability

Metric	AUPH	INSP
Gross margin	90.36%	86.13%
Operating margin	37.06%	6.02%
Net margin	100.84%	15.03%
ROE	51.09%	16.36%
ROIC	21.77%	6.33%

Growth (annualized)

Metric	AUPH	INSP
Revenue CAGR (5Y)	40.17%	38.69%
Total return CAGR (5Y)	-5.88%	-21.38%

Frequently asked

Which has the lower trailing P/E, AUPH or INSP?: AUPH has the lower trailing P/E: AUPH trades at 6.86 and INSP at 15.31. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, AUPH or INSP?: Over the past five years, AUPH grew revenue faster — AUPH at a 40.17% CAGR versus INSP at 38.69%.
Is AUPH or INSP more profitable?: AUPH runs the higher net margin — AUPH at 100.84% versus INSP at 15.03%.
How have AUPH and INSP total returns compared?: Over the past 5 years, AUPH delivered -5.88% and INSP delivered -21.38% annualized total return. Past performance doesn't predict future results.

Go deeper

Full AUPH analysis Full INSP analysis Interactive comparison tool

Dig into the metrics

Aurinia Pharmaceuticals P/E ratio Inspire Medical Systems P/E ratio Aurinia Pharmaceuticals ROE Inspire Medical Systems ROE Aurinia Pharmaceuticals operating margin Inspire Medical Systems operating margin Aurinia Pharmaceuticals revenue growth Inspire Medical Systems revenue growth Aurinia Pharmaceuticals free cash flow Inspire Medical Systems free cash flow

Aurinia Pharmaceuticals & Inspire Medical Systems appear in these rankings

Fastest Revenue Growth Stocks Highest ROE Stocks Highest ROIC Stocks Highest Operating Margin Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.