Alphatec Holdings, Inc. (ATEC) vs Syndax Pharmaceuticals, Inc. (SNDX)
A side-by-side comparison of Alphatec Holdings, Inc. and Syndax Pharmaceuticals, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
ATEC
Alphatec Holdings, Inc.
$10.54HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT
SNDX
Syndax Pharmaceuticals, Inc.
$17.37HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT
Total return — ATEC vs SNDX
growth of $100 · dividends reinvested · last 10yATEC +46.2% (+3.9%/yr)SNDX +13.6% (+1.3%/yr)ATEC compounded faster over this window
ATEC SNDX
ATEC vs SNDX: by the numbers
- •ATEC is the larger company ($1.62B vs $1.54B market cap).
- •Both run net losses; ATEC's is the smaller (-13.50% vs -87.60% net margin).
- •SNDX grew revenue faster over the past five years (178.06% vs 33.61% CAGR).
Metrics side by side
Valuation
| Metric | ATEC | SNDX |
|---|---|---|
| Forward P/E | 32.27 | N/A |
| P/S ratio | 1.99 | 6.11 |
| P/B ratio | N/A | 101.94 |
| EV / EBITDA | 56.65 | N/A |
| FCF yield | 0.26% | N/A |
Profitability
| Metric | ATEC | SNDX |
|---|---|---|
| Gross margin | 66.15% | 97.47% |
| Operating margin | -5.55% | -158.45% |
| Net margin | -13.50% | -87.60% |
| ROE | N/A | -1462.12% |
| ROIC | -7.32% | -32.15% |
Growth (annualized)
| Metric | ATEC | SNDX |
|---|---|---|
| Revenue CAGR (5Y) | 33.61% | 178.06% |
| Total return CAGR (5Y) | -2.26% | -0.01% |
Frequently asked
- Which has grown faster, ATEC or SNDX?
- Over the past five years, SNDX grew revenue faster — ATEC at a 33.61% CAGR versus SNDX at 178.06%.
- How have ATEC and SNDX total returns compared?
- Over the past 10 years, ATEC delivered 3.88% and SNDX delivered 1.04% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Alphatec ROESyndax Pharmaceuticals ROEAlphatec operating marginSyndax Pharmaceuticals operating marginAlphatec revenue growthSyndax Pharmaceuticals revenue growthAlphatec free cash flowSyndax Pharmaceuticals free cash flow
Alphatec & Syndax Pharmaceuticals appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.