Which has grown faster, ASTH or XNCR?

Over the past five years, ASTH grew revenue faster — ASTH at a 53.77% CAGR versus XNCR at 0.47%.

Is ASTH or XNCR more profitable?

ASTH runs the higher net margin — ASTH at 1.05% versus XNCR at -155.59%.

How have ASTH and XNCR total returns compared?

Over the past 10 years, ASTH delivered 25.17% and XNCR delivered 0.77% annualized total return. Past performance doesn't predict future results.

Astrana Health, Inc. (ASTH) vs Xencor, Inc. (XNCR)

A side-by-side comparison of Astrana Health, Inc. and Xencor, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

ASTH

Astrana Health, Inc.

$1.84B

$37.12HealthcareDelayed quote: Oct 6, 2026, 2:05 PM EDT

XNCR

Xencor, Inc.

$1.80B

$24.31HealthcareDelayed quote: Oct 6, 2026, 2:05 PM EDT

Total return — ASTH vs XNCR

growth of $100 · dividends reinvested · last 10y

ASTH +824.9% (+24.9%/yr)XNCR +10.1% (+1.0%/yr)ASTH compounded faster over this window

Log scale — wide-divergence pair

ASTH XNCR

ASTH vs XNCR: by the numbers

•ASTH is the larger company ($1.84B vs $1.80B market cap).
•ASTH is profitable (1.05% net margin) while XNCR runs a net loss (-155.59%).
•ASTH grew revenue faster over the past five years (53.77% vs 0.47% CAGR).

Metrics side by side

Valuation

Metric	ASTH	XNCR
P/E ratio	45.41	N/A
Forward P/E	26.55	N/A
P/S ratio	0.48	17.17
P/B ratio	2.22	3.58
EV / EBITDA	13.52	N/A
FCF yield	8.61%	N/A

Profitability

Metric	ASTH	XNCR
Gross margin	9.22%	91.63%
Operating margin	2.61%	-141.35%
Net margin	1.05%	-155.59%
ROE	4.88%	-32.46%
ROIC	4.13%	-33.60%

Growth (annualized)

Metric	ASTH	XNCR
Revenue CAGR (5Y)	53.77%	0.47%
EPS CAGR (5Y)	-15.06%	N/A
FCF CAGR (5Y)	18.35%	N/A
Total return CAGR (5Y)	-16.52%	-6.46%

Frequently asked

Which has grown faster, ASTH or XNCR?: Over the past five years, ASTH grew revenue faster — ASTH at a 53.77% CAGR versus XNCR at 0.47%.
Is ASTH or XNCR more profitable?: ASTH runs the higher net margin — ASTH at 1.05% versus XNCR at -155.59%.
How have ASTH and XNCR total returns compared?: Over the past 10 years, ASTH delivered 25.17% and XNCR delivered 0.77% annualized total return. Past performance doesn't predict future results.

Go deeper

Full ASTH analysis Full XNCR analysis Interactive comparison tool

Dig into the metrics

Astrana Health P/E ratio Astrana Health ROE Xencor ROE Astrana Health operating margin Xencor operating margin Astrana Health revenue growth Xencor revenue growth Astrana Health free cash flow Xencor free cash flow

Astrana Health & Xencor appear in these rankings

Fastest Revenue Growth Stocks Highest FCF Yield Stocks Highest 10-Year Total Return Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.