Which has grown faster, ASTH or SRPT?

Over the past five years, ASTH grew revenue faster — ASTH at a 53.77% CAGR versus SRPT at 26.90%.

Is ASTH or SRPT more profitable?

ASTH runs the higher net margin — ASTH at 1.05% versus SRPT at -6.93%.

How have ASTH and SRPT total returns compared?

Over the past 10 years, ASTH delivered 25.17% and SRPT delivered -11.94% annualized total return. Past performance doesn't predict future results.

Astrana Health, Inc. (ASTH) vs Sarepta Therapeutics, Inc. (SRPT)

A side-by-side comparison of Astrana Health, Inc. and Sarepta Therapeutics, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

ASTH

Astrana Health, Inc.

$1.84B

$37.12HealthcareDelayed quote: Oct 6, 2026, 2:05 PM EDT

SRPT

Sarepta Therapeutics, Inc.

$1.82B

$17.24HealthcareDelayed quote: Oct 6, 2026, 2:05 PM EDT

Total return — ASTH vs SRPT

growth of $100 · dividends reinvested · last 10y

ASTH +820.3% (+24.9%/yr)SRPT -71.5% (-11.8%/yr)ASTH compounded faster over this window

Log scale — wide-divergence pair

ASTH SRPT

ASTH vs SRPT: by the numbers

•ASTH is the larger company ($1.84B vs $1.82B market cap).
•ASTH is profitable (1.05% net margin) while SRPT runs a net loss (-6.93%).
•ASTH grew revenue faster over the past five years (53.77% vs 26.90% CAGR).

Metrics side by side

Valuation

Metric	ASTH	SRPT
P/E ratio	45.41	N/A
Forward P/E	26.55	5.36
P/S ratio	0.48	0.92
P/B ratio	2.22	1.19
EV / EBITDA	13.52	N/A
FCF yield	8.61%	N/A

Profitability

Metric	ASTH	SRPT
Gross margin	9.22%	58.56%
Operating margin	2.61%	-29.92%
Net margin	1.05%	-6.93%
ROE	4.88%	-8.95%
ROIC	4.13%	-5.33%

Growth (annualized)

Metric	ASTH	SRPT
Revenue CAGR (5Y)	53.77%	26.90%
EPS CAGR (5Y)	-15.06%	N/A
FCF CAGR (5Y)	18.35%	N/A
Total return CAGR (5Y)	-16.52%	-28.74%

Frequently asked

Which has grown faster, ASTH or SRPT?: Over the past five years, ASTH grew revenue faster — ASTH at a 53.77% CAGR versus SRPT at 26.90%.
Is ASTH or SRPT more profitable?: ASTH runs the higher net margin — ASTH at 1.05% versus SRPT at -6.93%.
How have ASTH and SRPT total returns compared?: Over the past 10 years, ASTH delivered 25.17% and SRPT delivered -11.94% annualized total return. Past performance doesn't predict future results.

Go deeper

Full ASTH analysis Full SRPT analysis Interactive comparison tool

Dig into the metrics

Astrana Health P/E ratio Astrana Health ROE Sarepta Therapeutics ROE Astrana Health operating margin Sarepta Therapeutics operating margin Astrana Health revenue growth Sarepta Therapeutics revenue growth Astrana Health free cash flow Sarepta Therapeutics free cash flow

Astrana Health & Sarepta Therapeutics appear in these rankings

Fastest Revenue Growth Stocks Highest FCF Yield Stocks Highest 10-Year Total Return Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.