Ascendis Pharma A/S (ASND) vs Tempus AI, Inc. (TEM)
A side-by-side comparison of Ascendis Pharma A/S and Tempus AI, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
ASND
Ascendis Pharma A/S
$228.03HealthcareDelayed quote: Oct 5, 2026, 4:00 PM EDT
TEM
Tempus AI, Inc.
$83.55HealthcareDelayed quote: Oct 5, 2026, 4:00 PM EDT
Total return — ASND vs TEM
growth of $100 · dividends reinvested · last 2yASND +78.7% (+33.7%/yr)TEM +107.6% (+44.1%/yr)TEM compounded faster over this window
ASND TEM
ASND vs TEM: by the numbers
- •TEM is the larger company ($14.64B vs $14.16B market cap).
- •ASND is profitable (71.08% net margin) while TEM runs a net loss (-17.77%).
- •ASND grew revenue faster over the past five years (189.92% vs 38.24% CAGR).
Metrics side by side
Valuation
| Metric | ASND | TEM |
|---|---|---|
| P/E ratio | 17.33 | N/A |
| P/S ratio | 11.59 | 10.22 |
| P/B ratio | 8.64 | 32.90 |
| EV / EBITDA | 93.79 | N/A |
| FCF yield | 2.73% | N/A |
Profitability
| Metric | ASND | TEM |
|---|---|---|
| Gross margin | 90.18% | 63.98% |
| Operating margin | -18.92% | -19.76% |
| Net margin | 71.08% | -17.77% |
| ROE | 52.97% | -57.18% |
| ROIC | 5.85% | -14.34% |
Growth (annualized)
| Metric | ASND | TEM |
|---|---|---|
| Revenue CAGR (5Y) | 189.92% | 38.24% |
| Total return CAGR (5Y) | 7.40% | N/A |
Frequently asked
- Which has grown faster, ASND or TEM?
- Over the past five years, ASND grew revenue faster — ASND at a 189.92% CAGR versus TEM at 38.24%.
- Is ASND or TEM more profitable?
- ASND runs the higher net margin — ASND at 71.08% versus TEM at -17.77%.
Go deeper
Dig into the metrics
Ascendis Pharma A/S P/E ratioAscendis Pharma A/S ROETempus AI ROEAscendis Pharma A/S operating marginTempus AI operating marginAscendis Pharma A/S revenue growthTempus AI revenue growthAscendis Pharma A/S free cash flowTempus AI free cash flow
Ascendis Pharma A/S & Tempus AI appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.