Which has the lower trailing P/E, ASND or NBIX?

ASND has the lower trailing P/E: ASND trades at 17.18 and NBIX at 21.34. P/E is one valuation measure and does not by itself establish which business is cheaper.

Which has grown faster, ASND or NBIX?

Over the past five years, ASND grew revenue faster — ASND at a 189.92% CAGR versus NBIX at 26.74%.

Is ASND or NBIX more profitable?

ASND runs the higher net margin — ASND at 71.08% versus NBIX at 20.91%.

How have ASND and NBIX total returns compared?

Over the past 10 years, ASND delivered 27.41% and NBIX delivered 10.90% annualized total return. Past performance doesn't predict future results.

Ascendis Pharma A/S (ASND) vs Neurocrine Biosciences, Inc. (NBIX)

A side-by-side comparison of Ascendis Pharma A/S and Neurocrine Biosciences, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

ASND

Ascendis Pharma A/S

$14.04B

$226.05HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT

NBIX

Neurocrine Biosciences, Inc.

$14.63B

$145.51HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT

Total return — ASND vs NBIX

growth of $100 · dividends reinvested · last 10y

ASND +1027.2% (+27.4%/yr)NBIX +186.9% (+11.1%/yr)ASND compounded faster over this window

ASND NBIX

ASND vs NBIX: by the numbers

•NBIX is the larger company ($14.63B vs $14.04B market cap).
•ASND trades at the lower trailing earnings multiple (17.18 vs 21.34 P/E), one valuation lens rather than an overall verdict.
•ASND converts more revenue to profit (71.08% vs 20.91% net margin).
•ASND grew revenue faster over the past five years (189.92% vs 26.74% CAGR).

Metrics side by side

Valuation

Metric	ASND	NBIX
P/E ratio	17.18	21.34
Forward P/E	N/A	20.60
PEG ratio	N/A	9.12
P/S ratio	11.49	4.34
P/B ratio	8.56	3.96
EV / EBITDA	92.96	17.58
FCF yield	2.76%	5.92%

Profitability

Metric	ASND	NBIX
Gross margin	90.18%	97.97%
Operating margin	-18.92%	23.38%
Net margin	71.08%	20.91%
ROE	52.97%	19.10%
ROIC	5.85%	13.20%

Growth (annualized)

Metric	ASND	NBIX
Revenue CAGR (5Y)	189.92%	26.74%
EPS CAGR (5Y)	N/A	1.94%
FCF CAGR (5Y)	N/A	28.69%
Total return CAGR (5Y)	7.40%	7.56%

Frequently asked

Which has the lower trailing P/E, ASND or NBIX?: ASND has the lower trailing P/E: ASND trades at 17.18 and NBIX at 21.34. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, ASND or NBIX?: Over the past five years, ASND grew revenue faster — ASND at a 189.92% CAGR versus NBIX at 26.74%.
Is ASND or NBIX more profitable?: ASND runs the higher net margin — ASND at 71.08% versus NBIX at 20.91%.
How have ASND and NBIX total returns compared?: Over the past 10 years, ASND delivered 27.41% and NBIX delivered 10.90% annualized total return. Past performance doesn't predict future results.

Go deeper

Full ASND analysis Full NBIX analysis Interactive comparison tool

Dig into the metrics

Ascendis Pharma A/S P/E ratio Neurocrine Biosciences P/E ratio Ascendis Pharma A/S ROE Neurocrine Biosciences ROE Ascendis Pharma A/S operating margin Neurocrine Biosciences operating margin Ascendis Pharma A/S revenue growth Neurocrine Biosciences revenue growth Ascendis Pharma A/S free cash flow Neurocrine Biosciences free cash flow

Ascendis Pharma A/S & Neurocrine Biosciences appear in these rankings

Fastest Revenue Growth Stocks Highest ROE Stocks Highest FCF Yield Stocks Highest 10-Year Total Return Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.