Which has the lower trailing P/E, ASND or ICLR?

ASND has the lower trailing P/E: ASND trades at 17.33 and ICLR at 39.51. P/E is one valuation measure and does not by itself establish which business is cheaper.

Which has grown faster, ASND or ICLR?

Over the past five years, ASND grew revenue faster — ASND at a 189.92% CAGR versus ICLR at 20.93%.

Is ASND or ICLR more profitable?

ASND runs the higher net margin — ASND at 71.08% versus ICLR at 3.99%.

How have ASND and ICLR total returns compared?

Over the past 10 years, ASND delivered 27.41% and ICLR delivered 8.07% annualized total return. Past performance doesn't predict future results.

Ascendis Pharma A/S (ASND) vs ICON Public Limited Company (ICLR)

A side-by-side comparison of Ascendis Pharma A/S and ICON Public Limited Company across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

ASND

Ascendis Pharma A/S

$14.16B

$228.03HealthcareDelayed quote: Oct 5, 2026, 4:00 PM EDT

ICLR

ICON Public Limited Company

$12.89B

$168.33HealthcareDelayed quote: Oct 5, 2026, 4:00 PM EDT

Total return — ASND vs ICLR

growth of $100 · dividends reinvested · last 10y

ASND +1027.2% (+27.4%/yr)ICLR +121.1% (+8.3%/yr)ASND compounded faster over this window

Log scale — wide-divergence pair

ASND ICLR

ASND vs ICLR: by the numbers

•ASND is the larger company ($14.16B vs $12.89B market cap).
•ASND trades at the lower trailing earnings multiple (17.33 vs 39.51 P/E), one valuation lens rather than an overall verdict.
•ASND converts more revenue to profit (71.08% vs 3.99% net margin).
•ASND grew revenue faster over the past five years (189.92% vs 20.93% CAGR).

Metrics side by side

Valuation

Metric	ASND	ICLR
P/E ratio	17.33	39.51
Forward P/E	N/A	15.90
P/S ratio	11.59	1.56
P/B ratio	8.64	1.37
EV / EBITDA	93.79	10.94
FCF yield	2.73%	10.44%

Profitability

Metric	ASND	ICLR
Gross margin	90.18%	21.85%
Operating margin	-18.92%	10.15%
Net margin	71.08%	3.99%
ROE	52.97%	3.51%
ROIC	5.85%	4.80%

Growth (annualized)

Metric	ASND	ICLR
Revenue CAGR (5Y)	189.92%	20.93%
EPS CAGR (5Y)	N/A	-14.23%
FCF CAGR (5Y)	N/A	22.10%
Total return CAGR (5Y)	7.40%	-8.50%

Frequently asked

Which has the lower trailing P/E, ASND or ICLR?: ASND has the lower trailing P/E: ASND trades at 17.33 and ICLR at 39.51. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, ASND or ICLR?: Over the past five years, ASND grew revenue faster — ASND at a 189.92% CAGR versus ICLR at 20.93%.
Is ASND or ICLR more profitable?: ASND runs the higher net margin — ASND at 71.08% versus ICLR at 3.99%.
How have ASND and ICLR total returns compared?: Over the past 10 years, ASND delivered 27.41% and ICLR delivered 8.07% annualized total return. Past performance doesn't predict future results.

Go deeper

Full ASND analysis Full ICLR analysis Interactive comparison tool

Dig into the metrics

Ascendis Pharma A/S P/E ratio ICON Public P/E ratio Ascendis Pharma A/S ROE ICON Public ROE Ascendis Pharma A/S operating margin ICON Public operating margin Ascendis Pharma A/S revenue growth ICON Public revenue growth Ascendis Pharma A/S free cash flow ICON Public free cash flow

Ascendis Pharma A/S & ICON Public appear in these rankings

Fastest Revenue Growth Stocks Highest ROE Stocks Highest FCF Yield Stocks Highest 10-Year Total Return Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.