Which has the lower trailing P/E, ASND or HALO?

ASND has the lower trailing P/E: ASND trades at 17.23 and HALO at 32.75. P/E is one valuation measure and does not by itself establish which business is cheaper.

Which has grown faster, ASND or HALO?

Over the past five years, ASND grew revenue faster — ASND at a 189.92% CAGR versus HALO at 32.18%.

Is ASND or HALO more profitable?

ASND runs the higher net margin — ASND at 71.08% versus HALO at 24.86%.

How have ASND and HALO total returns compared?

Over the past 10 years, ASND delivered 27.41% and HALO delivered 24.30% annualized total return. Past performance doesn't predict future results.

Ascendis Pharma A/S (ASND) vs Halozyme Therapeutics, Inc. (HALO)

A side-by-side comparison of Ascendis Pharma A/S and Halozyme Therapeutics, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

ASND

Ascendis Pharma A/S

$14.08B

$226.70HealthcareDelayed quote: Oct 6, 2026, 9:40 AM EDT

HALO

Halozyme Therapeutics, Inc.

$13.01B

$109.70HealthcareDelayed quote: Oct 6, 2026, 9:40 AM EDT

Total return — ASND vs HALO

growth of $100 · dividends reinvested · last 10y

ASND +1027.2% (+27.4%/yr)HALO +779.9% (+24.3%/yr)ASND compounded faster over this window

ASND HALO

ASND vs HALO: by the numbers

•ASND is the larger company ($14.08B vs $13.01B market cap).
•ASND trades at the lower trailing earnings multiple (17.23 vs 32.75 P/E), one valuation lens rather than an overall verdict.
•ASND converts more revenue to profit (71.08% vs 24.86% net margin).
•ASND grew revenue faster over the past five years (189.92% vs 32.18% CAGR).

Metrics side by side

Valuation

Metric	ASND	HALO
P/E ratio	17.23	32.75
Forward P/E	N/A	13.04
PEG ratio	N/A	1.43
P/S ratio	11.52	7.82
P/B ratio	8.59	90.65
EV / EBITDA	93.23	14.22
FCF yield	2.75%	6.20%

Profitability

Metric	ASND	HALO
Gross margin	90.18%	78.18%
Operating margin	-18.92%	56.77%
Net margin	71.08%	24.86%
ROE	52.97%	288.13%
ROIC	5.85%	27.42%

Growth (annualized)

Metric	ASND	HALO
Revenue CAGR (5Y)	189.92%	32.18%
EPS CAGR (5Y)	N/A	22.68%
FCF CAGR (5Y)	N/A	40.08%
Total return CAGR (5Y)	7.40%	22.18%

Frequently asked

Which has the lower trailing P/E, ASND or HALO?: ASND has the lower trailing P/E: ASND trades at 17.23 and HALO at 32.75. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, ASND or HALO?: Over the past five years, ASND grew revenue faster — ASND at a 189.92% CAGR versus HALO at 32.18%.
Is ASND or HALO more profitable?: ASND runs the higher net margin — ASND at 71.08% versus HALO at 24.86%.
How have ASND and HALO total returns compared?: Over the past 10 years, ASND delivered 27.41% and HALO delivered 24.30% annualized total return. Past performance doesn't predict future results.

Go deeper

Full ASND analysis Full HALO analysis Interactive comparison tool

Dig into the metrics

Ascendis Pharma A/S P/E ratio Halozyme Therapeutics P/E ratio Ascendis Pharma A/S ROE Halozyme Therapeutics ROE Ascendis Pharma A/S operating margin Halozyme Therapeutics operating margin Ascendis Pharma A/S revenue growth Halozyme Therapeutics revenue growth Ascendis Pharma A/S free cash flow Halozyme Therapeutics free cash flow

Ascendis Pharma A/S & Halozyme Therapeutics appear in these rankings

Fastest Revenue Growth Stocks Highest ROE Stocks Highest ROIC Stocks Highest Operating Margin Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.