Assembly Biosciences, Inc. (ASMB) vs Shoulder Innovations, Inc. (SI)
A side-by-side comparison of Assembly Biosciences, Inc. and Shoulder Innovations, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
ASMB
Assembly Biosciences, Inc.
$21.98HealthcareDelayed quote: Oct 6, 2026, 1:00 PM EDT
SI
Shoulder Innovations, Inc.
$19.77HealthcareDelayed quote: Oct 6, 2026, 12:54 PM EDT
Total return — ASMB vs SI
growth of $100 · dividends reinvested · last 1yASMB +16.6% (+16.6%/yr)SI +30.2% (+30.2%/yr)SI compounded faster over this window
ASMB SI
ASMB vs SI: by the numbers
- •ASMB is the larger company ($435M vs $410M market cap).
- •Both run net losses; ASMB's is the smaller (-0.06% vs -58.33% net margin).
Metrics side by side
Valuation
| Metric | ASMB | SI |
|---|---|---|
| P/E ratio | 39.95 | N/A |
| P/S ratio | 5.82 | 6.83 |
| P/B ratio | 1.42 | 3.30 |
Profitability
| Metric | ASMB | SI |
|---|---|---|
| Gross margin | 99.82% | 77.34% |
| Operating margin | -11.75% | -58.53% |
| Net margin | -0.06% | -58.33% |
| ROE | -0.01% | -28.18% |
| ROIC | -2.86% | -25.26% |
Growth (annualized)
| Metric | ASMB | SI |
|---|---|---|
| Revenue CAGR (5Y) | -1.78% | N/A |
| Total return CAGR (5Y) | -10.66% | N/A |
Go deeper
Dig into the metrics
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.