Arrowhead Pharmaceuticals, Inc. (ARWR) vs Praxis Precision Medicines, Inc. (PRAX)
A side-by-side comparison of Arrowhead Pharmaceuticals, Inc. and Praxis Precision Medicines, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
ARWR
Arrowhead Pharmaceuticals, Inc.
$61.54HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT
PRAX
Praxis Precision Medicines, Inc.
$280.39HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT
Total return — ARWR vs PRAX
growth of $100 · dividends reinvested · last 6yARWR +26.3% (+4.0%/yr)PRAX -32.0% (-6.2%/yr)ARWR compounded faster over this window
ARWR PRAX
ARWR vs PRAX: by the numbers
- •ARWR is the larger company ($8.67B vs $7.82B market cap).
- •Both run net losses; PRAX's is the smaller (0.00% vs -47.79% net margin).
Metrics side by side
Valuation
| Metric | ARWR | PRAX |
|---|---|---|
| P/S ratio | 12.95 | N/A |
| P/B ratio | 18.62 | 5.83 |
Profitability
| Metric | ARWR | PRAX |
|---|---|---|
| Gross margin | 100.00% | 0.00% |
| Operating margin | 11.86% | 0.00% |
| Net margin | -47.79% | 0.00% |
| ROE | -68.73% | -25.29% |
| ROIC | -12.12% | -28.18% |
Growth (annualized)
| Metric | ARWR | PRAX |
|---|---|---|
| Revenue CAGR (5Y) | 44.14% | N/A |
| Total return CAGR (5Y) | 0.75% | -0.21% |
Frequently asked
- How have ARWR and PRAX total returns compared?
- Over the past 5 years, ARWR delivered 0.75% and PRAX delivered -0.21% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Arrowhead Pharmaceuticals ROEPraxis Precision Medicines ROEArrowhead Pharmaceuticals operating marginPraxis Precision Medicines operating marginArrowhead Pharmaceuticals revenue growthPraxis Precision Medicines revenue growthArrowhead Pharmaceuticals free cash flowPraxis Precision Medicines free cash flow
Arrowhead Pharmaceuticals & Praxis Precision Medicines appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.