Arrowhead Pharmaceuticals, Inc. (ARWR) vs Vaxcyte, Inc. (PCVX)
A side-by-side comparison of Arrowhead Pharmaceuticals, Inc. and Vaxcyte, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
ARWR
Arrowhead Pharmaceuticals, Inc.
$61.99HealthcareDelayed quote: Oct 6, 2026, 1:00 PM EDT
PCVX
Vaxcyte, Inc.
$65.70HealthcareDelayed quote: Oct 6, 2026, 1:00 PM EDT
Total return — ARWR vs PCVX
growth of $100 · dividends reinvested · last 6yARWR +90.5% (+11.3%/yr)PCVX +182.3% (+18.9%/yr)PCVX compounded faster over this window
ARWR PCVX
ARWR vs PCVX: by the numbers
- •PCVX is the larger company ($9.49B vs $8.73B market cap).
- •Both run net losses; PCVX's is the smaller (0.00% vs -47.79% net margin).
Metrics side by side
Valuation
| Metric | ARWR | PCVX |
|---|---|---|
| P/S ratio | 13.04 | N/A |
| P/B ratio | 18.76 | 3.44 |
Profitability
| Metric | ARWR | PCVX |
|---|---|---|
| Gross margin | 100.00% | 0.00% |
| Operating margin | 11.86% | 0.00% |
| Net margin | -47.79% | 0.00% |
| ROE | -68.73% | -38.59% |
| ROIC | -12.12% | -40.65% |
Growth (annualized)
| Metric | ARWR | PCVX |
|---|---|---|
| Revenue CAGR (5Y) | 44.14% | N/A |
| Total return CAGR (5Y) | 0.75% | 25.08% |
Frequently asked
- How have ARWR and PCVX total returns compared?
- Over the past 5 years, ARWR delivered 0.75% and PCVX delivered 25.08% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Arrowhead Pharmaceuticals ROEVaxcyte ROEArrowhead Pharmaceuticals operating marginVaxcyte operating marginArrowhead Pharmaceuticals revenue growthVaxcyte revenue growthArrowhead Pharmaceuticals free cash flowVaxcyte free cash flow
Arrowhead Pharmaceuticals & Vaxcyte appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.