Which has the lower trailing P/E, ARVN or ASMB?

ASMB has the lower trailing P/E: ARVN trades at 46.37 and ASMB at 40.70. P/E is one valuation measure and does not by itself establish which business is cheaper.

Which has grown faster, ARVN or ASMB?

Over the past five years, ARVN grew revenue faster — ARVN at a 72.38% CAGR versus ASMB at -1.78%.

Is ARVN or ASMB more profitable?

ARVN runs the higher net margin — ARVN at 2.94% versus ASMB at -0.06%.

How have ARVN and ASMB total returns compared?

Over the past 5 years, ARVN delivered -38.16% and ASMB delivered -10.66% annualized total return. Past performance doesn't predict future results.

Arvinas, Inc. (ARVN) vs Assembly Biosciences, Inc. (ASMB)

A side-by-side comparison of Arvinas, Inc. and Assembly Biosciences, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

ARVN

Arvinas, Inc.

$479M

$7.42HealthcareDelayed quote: Oct 6, 2026, 10:05 AM EDT

ASMB

Assembly Biosciences, Inc.

$444M

$22.39HealthcareDelayed quote: Oct 6, 2026, 10:05 AM EDT

Total return — ARVN vs ASMB

growth of $100 · dividends reinvested · last 8y

ARVN -53.5% (-9.1%/yr)ASMB -94.6% (-30.6%/yr)ARVN compounded faster over this window

Log scale — wide-divergence pair

ARVN ASMB

ARVN vs ASMB: by the numbers

•ARVN is the larger company ($479M vs $444M market cap).
•ASMB trades at the lower trailing earnings multiple (40.70 vs 46.37 P/E), one valuation lens rather than an overall verdict.
•ARVN is profitable (2.94% net margin) while ASMB runs a net loss (-0.06%).
•ARVN grew revenue faster over the past five years (72.38% vs -1.78% CAGR).

Metrics side by side

Valuation

Metric	ARVN	ASMB
P/E ratio	46.37	40.70
P/S ratio	1.51	5.93
P/B ratio	0.85	1.45

Profitability

Metric	ARVN	ASMB
Gross margin	96.43%	99.82%
Operating margin	-43.75%	-11.75%
Net margin	2.94%	-0.06%
ROE	1.65%	-0.01%
ROIC	-2.19%	-2.86%

Growth (annualized)

Metric	ARVN	ASMB
Revenue CAGR (5Y)	72.38%	-1.78%
Total return CAGR (5Y)	-38.16%	-10.66%

Frequently asked

Which has the lower trailing P/E, ARVN or ASMB?: ASMB has the lower trailing P/E: ARVN trades at 46.37 and ASMB at 40.70. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, ARVN or ASMB?: Over the past five years, ARVN grew revenue faster — ARVN at a 72.38% CAGR versus ASMB at -1.78%.
Is ARVN or ASMB more profitable?: ARVN runs the higher net margin — ARVN at 2.94% versus ASMB at -0.06%.
How have ARVN and ASMB total returns compared?: Over the past 5 years, ARVN delivered -38.16% and ASMB delivered -10.66% annualized total return. Past performance doesn't predict future results.

Go deeper

Full ARVN analysis Full ASMB analysis Interactive comparison tool

Dig into the metrics

Arvinas P/E ratio Assembly Biosciences P/E ratio Arvinas ROE Assembly Biosciences ROE Arvinas operating margin Assembly Biosciences operating margin Arvinas revenue growth Assembly Biosciences revenue growth Arvinas free cash flow Assembly Biosciences free cash flow

Arvinas & Assembly Biosciences appear in these rankings

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Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.