Is ARQT or IDYA more profitable?

ARQT runs the higher net margin — ARQT at 6.15% versus IDYA at -74.75%.

How have ARQT and IDYA total returns compared?

Over the past 5 years, ARQT delivered -0.28% and IDYA delivered 7.32% annualized total return. Past performance doesn't predict future results.

Arcutis Biotherapeutics, Inc. (ARQT) vs IDEAYA Biosciences, Inc. (IDYA)

A side-by-side comparison of Arcutis Biotherapeutics, Inc. and IDEAYA Biosciences, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

ARQT

Arcutis Biotherapeutics, Inc.

$3.04B

$24.33HealthcareDelayed quote: Oct 6, 2026, 10:25 AM EDT

IDYA

IDEAYA Biosciences, Inc.

$3.49B

$36.67HealthcareDelayed quote: Oct 6, 2026, 10:25 AM EDT

Total return — ARQT vs IDYA

growth of $100 · dividends reinvested · last 7y

ARQT +15.4% (+2.1%/yr)IDYA +345.1% (+23.8%/yr)IDYA compounded faster over this window

ARQT IDYA

ARQT vs IDYA: by the numbers

•IDYA is the larger company ($3.49B vs $3.04B market cap).
•ARQT is profitable (6.15% net margin) while IDYA runs a net loss (-74.75%).

Metrics side by side

Valuation

Metric	ARQT	IDYA
P/E ratio	116.69	N/A
Forward P/E	48.94	N/A
P/S ratio	6.56	14.89
P/B ratio	13.80	2.91
EV / EBITDA	83.95	N/A
FCF yield	1.29%	N/A

Profitability

Metric	ARQT	IDYA
Gross margin	91.14%	-43.89%
Operating margin	-3.25%	-72.84%
Net margin	6.15%	-74.75%
ROE	12.93%	-14.60%
ROIC	9.95%	-17.68%

Growth (annualized)

Metric	ARQT	IDYA
Revenue CAGR (5Y)	N/A	45.80%
Total return CAGR (5Y)	-0.28%	7.32%

Frequently asked

Is ARQT or IDYA more profitable?: ARQT runs the higher net margin — ARQT at 6.15% versus IDYA at -74.75%.
How have ARQT and IDYA total returns compared?: Over the past 5 years, ARQT delivered -0.28% and IDYA delivered 7.32% annualized total return. Past performance doesn't predict future results.

Go deeper

Full ARQT analysis Full IDYA analysis Interactive comparison tool

Dig into the metrics

Arcutis Biotherapeutics P/E ratio Arcutis Biotherapeutics ROE IDEAYA Biosciences ROE Arcutis Biotherapeutics operating margin IDEAYA Biosciences operating margin Arcutis Biotherapeutics revenue growth IDEAYA Biosciences revenue growth Arcutis Biotherapeutics free cash flow IDEAYA Biosciences free cash flow

Arcutis Biotherapeutics & IDEAYA Biosciences appear in these rankings

Fastest Revenue Growth Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.