Arcutis Biotherapeutics, Inc. (ARQT) vs Dyne Therapeutics, Inc. (DYN)

A side-by-side comparison of Arcutis Biotherapeutics, Inc. and Dyne Therapeutics, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

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Total return — ARQT vs DYN

growth of $100 · dividends reinvested · last 6y
ARQT -2.1% (-0.4%/yr)DYN -35.4% (-7.0%/yr)ARQT compounded faster over this window
050100150200Start $100202120222023202420252026$98$65
ARQT DYN

ARQT vs DYN: by the numbers

  • •ARQT is the larger company ($3.15B vs $2.88B market cap).
  • •ARQT is profitable (6.15% net margin) while DYN runs a net loss (0.00%).

Metrics side by side

Valuation

MetricARQTDYN
P/E ratio120.62N/A
Forward P/E50.59N/A
P/S ratio6.78N/A
P/B ratio14.264.11
EV / EBITDA86.71N/A
FCF yield1.24%N/A

Profitability

MetricARQTDYN
Gross margin91.14%0.00%
Operating margin-3.25%0.00%
Net margin6.15%0.00%
ROE12.93%-73.97%
ROIC9.95%-58.28%

Growth (annualized)

MetricARQTDYN
Total return CAGR (5Y)-0.28%-0.38%

Frequently asked

Is ARQT or DYN more profitable?
ARQT runs the higher net margin — ARQT at 6.15% versus DYN at 0.00%.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.