Ardelyx, Inc. (ARDX) vs Lexicon Pharmaceuticals, Inc. (LXRX)
A side-by-side comparison of Ardelyx, Inc. and Lexicon Pharmaceuticals, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
ARDX
Ardelyx, Inc.
$3.30HealthcareDelayed quote: Oct 6, 2026, 11:50 AM EDT
LXRX
Lexicon Pharmaceuticals, Inc.
$1.78HealthcareDelayed quote: Oct 6, 2026, 11:45 AM EDT
Total return — ARDX vs LXRX
growth of $100 · dividends reinvested · last 10yARDX -1.5% (-0.1%/yr)LXRX -90.4% (-20.9%/yr)ARDX compounded faster over this window
Log scale — wide-divergence pair
ARDX LXRX
ARDX vs LXRX: by the numbers
- •ARDX is the larger company ($816M vs $788M market cap).
- •Both run net losses; ARDX's is the smaller (-12.35% vs -147.38% net margin).
- •ARDX grew revenue faster over the past five years (105.14% vs 42.36% CAGR).
Metrics side by side
Valuation
| Metric | ARDX | LXRX |
|---|---|---|
| P/S ratio | 1.81 | 19.01 |
| P/B ratio | 5.48 | 4.52 |
Profitability
| Metric | ARDX | LXRX |
|---|---|---|
| Gross margin | 93.96% | 98.85% |
| Operating margin | -7.86% | -98.21% |
| Net margin | -12.35% | -147.38% |
| ROE | -37.38% | -35.02% |
| ROIC | -7.99% | -23.16% |
Growth (annualized)
| Metric | ARDX | LXRX |
|---|---|---|
| Revenue CAGR (5Y) | 105.14% | 42.36% |
| Total return CAGR (5Y) | 20.95% | -18.54% |
Frequently asked
- Which has grown faster, ARDX or LXRX?
- Over the past five years, ARDX grew revenue faster — ARDX at a 105.14% CAGR versus LXRX at 42.36%.
- How have ARDX and LXRX total returns compared?
- Over the past 10 years, ARDX delivered -0.20% and LXRX delivered -21.03% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Ardelyx ROELexicon Pharmaceuticals ROEArdelyx operating marginLexicon Pharmaceuticals operating marginArdelyx revenue growthLexicon Pharmaceuticals revenue growthArdelyx free cash flowLexicon Pharmaceuticals free cash flow
Ardelyx & Lexicon Pharmaceuticals appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.