How have ARDX and JBIO total returns compared?

Over the past 5 years, ARDX delivered 20.95% and JBIO delivered -52.65% annualized total return. Past performance doesn't predict future results.

Ardelyx, Inc. (ARDX) vs Jade Biosciences, Inc. (JBIO)

A side-by-side comparison of Ardelyx, Inc. and Jade Biosciences, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

ARDX

Ardelyx, Inc.

$813M

$3.29HealthcareDelayed quote: Oct 6, 2026, 10:10 AM EDT

JBIO

Jade Biosciences, Inc.

$819M

$13.45HealthcareDelayed quote: Oct 6, 2026, 10:10 AM EDT

Total return — ARDX vs JBIO

growth of $100 · dividends reinvested · last 5y

ARDX +70.4% (+11.2%/yr)JBIO -97.8% (-53.5%/yr)ARDX compounded faster over this window

Log scale — wide-divergence pair

ARDX JBIO

ARDX vs JBIO: by the numbers

•JBIO is the larger company ($819M vs $813M market cap).
•Both run net losses; JBIO's is the smaller (0.00% vs -12.35% net margin).

Metrics side by side

Valuation

Metric	ARDX	JBIO
P/S ratio	1.80	N/A
P/B ratio	5.45	1.86

Profitability

Metric	ARDX	JBIO
Gross margin	93.96%	0.00%
Operating margin	-7.86%	0.00%
Net margin	-12.35%	0.00%
ROE	-37.38%	-34.83%
ROIC	-7.99%	-37.39%

Growth (annualized)

Metric	ARDX	JBIO
Revenue CAGR (5Y)	105.14%	N/A
Total return CAGR (5Y)	20.95%	-52.65%

Frequently asked

How have ARDX and JBIO total returns compared?: Over the past 5 years, ARDX delivered 20.95% and JBIO delivered -52.65% annualized total return. Past performance doesn't predict future results.

Go deeper

Full ARDX analysis Full JBIO analysis Interactive comparison tool

Dig into the metrics

Ardelyx ROE Jade Biosciences ROE Ardelyx operating margin Jade Biosciences operating margin Ardelyx revenue growth Jade Biosciences revenue growth Ardelyx free cash flow Jade Biosciences free cash flow

Ardelyx & Jade Biosciences appear in these rankings

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Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.