Ardelyx, Inc. (ARDX) vs Gyre Therapeutics, Inc. (GYRE)
A side-by-side comparison of Ardelyx, Inc. and Gyre Therapeutics, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
ARDX
Ardelyx, Inc.
$3.34HealthcareDelayed quote: Oct 6, 2026, 11:25 AM EDT
GYRE
Gyre Therapeutics, Inc.
$7.16HealthcareDelayed quote: Oct 6, 2026, 11:25 AM EDT
Total return — ARDX vs GYRE
growth of $100 · dividends reinvested · last 10yARDX -1.5% (-0.1%/yr)GYRE -79.5% (-14.6%/yr)ARDX compounded faster over this window
ARDX GYRE
ARDX vs GYRE: by the numbers
- •ARDX is the larger company ($824M vs $798M market cap).
- •Both run net losses; ARDX's is the smaller (-12.35% vs -14.52% net margin).
- •ARDX grew revenue faster over the past five years (105.14% vs 84.92% CAGR).
Metrics side by side
Valuation
| Metric | ARDX | GYRE |
|---|---|---|
| P/S ratio | 1.83 | 6.69 |
| P/B ratio | 5.53 | 7.40 |
Profitability
| Metric | ARDX | GYRE |
|---|---|---|
| Gross margin | 93.96% | 94.30% |
| Operating margin | -7.86% | 9.86% |
| Net margin | -12.35% | -14.52% |
| ROE | -37.38% | -13.30% |
| ROIC | -7.99% | -9.77% |
Growth (annualized)
| Metric | ARDX | GYRE |
|---|---|---|
| Revenue CAGR (5Y) | 105.14% | 84.92% |
| Total return CAGR (5Y) | 20.95% | -0.34% |
Frequently asked
- Which has grown faster, ARDX or GYRE?
- Over the past five years, ARDX grew revenue faster — ARDX at a 105.14% CAGR versus GYRE at 84.92%.
- How have ARDX and GYRE total returns compared?
- Over the past 10 years, ARDX delivered -0.20% and GYRE delivered -14.92% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Ardelyx ROEGyre Therapeutics ROEArdelyx operating marginGyre Therapeutics operating marginArdelyx revenue growthGyre Therapeutics revenue growthArdelyx free cash flowGyre Therapeutics free cash flow
Ardelyx & Gyre Therapeutics appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.