Ardelyx, Inc. (ARDX) vs Monte Rosa Therapeutics, Inc. (GLUE)
A side-by-side comparison of Ardelyx, Inc. and Monte Rosa Therapeutics, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
ARDX
Ardelyx, Inc.
$3.28HealthcareDelayed quote: Oct 6, 2026, 3:35 PM EDT
GLUE
Monte Rosa Therapeutics, Inc.
$9.85HealthcareDelayed quote: Oct 6, 2026, 3:35 PM EDT
Total return — ARDX vs GLUE
growth of $100 · dividends reinvested · last 5yARDX +89.4% (+13.6%/yr)GLUE -51.5% (-13.5%/yr)ARDX compounded faster over this window
ARDX GLUE
ARDX vs GLUE: by the numbers
- •GLUE is the larger company ($832M vs $810M market cap).
- •Both run net losses; ARDX's is the smaller (-12.35% vs -560.85% net margin).
Metrics side by side
Valuation
| Metric | ARDX | GLUE |
|---|---|---|
| P/S ratio | 1.80 | 28.97 |
| P/B ratio | 5.44 | 1.71 |
Profitability
| Metric | ARDX | GLUE |
|---|---|---|
| Gross margin | 93.96% | 92.94% |
| Operating margin | -7.86% | -43.83% |
| Net margin | -12.35% | -560.85% |
| ROE | -37.38% | -33.06% |
| ROIC | -7.99% | -28.69% |
Growth (annualized)
| Metric | ARDX | GLUE |
|---|---|---|
| Revenue CAGR (5Y) | 105.14% | N/A |
| Total return CAGR (5Y) | 20.95% | -12.32% |
Frequently asked
- How have ARDX and GLUE total returns compared?
- Over the past 5 years, ARDX delivered 20.95% and GLUE delivered -12.32% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Ardelyx ROEMonte Rosa Therapeutics ROEArdelyx operating marginMonte Rosa Therapeutics operating marginArdelyx revenue growthMonte Rosa Therapeutics revenue growthArdelyx free cash flowMonte Rosa Therapeutics free cash flow
Ardelyx & Monte Rosa Therapeutics appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.