Aquestive Therapeutics, Inc. (AQST) vs Ironwood Pharmaceuticals, Inc. (IRWD)
A side-by-side comparison of Aquestive Therapeutics, Inc. and Ironwood Pharmaceuticals, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
AQST
Aquestive Therapeutics, Inc.
$4.57HealthcareDelayed quote: Oct 6, 2026, 12:00 PM EDT
IRWD
Ironwood Pharmaceuticals, Inc.
$3.65HealthcareDelayed quote: Oct 6, 2026, 12:00 PM EDT
Total return — AQST vs IRWD
growth of $100 · dividends reinvested · last 8yAQST -71.5% (-14.5%/yr)IRWD -81.8% (-19.2%/yr)AQST compounded faster over this window
AQST IRWD
AQST vs IRWD: by the numbers
- •IRWD is the larger company ($601M vs $573M market cap).
- •IRWD is profitable (33.36% net margin) while AQST runs a net loss (-144.63%).
- •Both shrank revenue over the past five years; AQST's decline was smaller (-0.58% vs -1.18% CAGR).
Metrics side by side
Valuation
| Metric | AQST | IRWD |
|---|---|---|
| P/E ratio | N/A | 4.76 |
| Forward P/E | N/A | 2.98 |
| P/S ratio | 10.60 | 1.54 |
| EV / EBITDA | N/A | 3.86 |
| FCF yield | N/A | 30.88% |
Profitability
| Metric | AQST | IRWD |
|---|---|---|
| Gross margin | 67.04% | 99.76% |
| Operating margin | -156.36% | 40.10% |
| Net margin | -144.63% | 33.36% |
| ROIC | -45.62% | 58.60% |
Growth (annualized)
| Metric | AQST | IRWD |
|---|---|---|
| Revenue CAGR (5Y) | -0.58% | -1.18% |
| EPS CAGR (5Y) | N/A | -25.87% |
| FCF CAGR (5Y) | N/A | -3.98% |
| Total return CAGR (5Y) | 2.24% | -22.82% |
Frequently asked
- Which has grown faster, AQST or IRWD?
- Neither grew: over the past five years both shrank revenue, with AQST's decline the smaller — AQST at a -0.58% CAGR versus IRWD at -1.18%.
- Is AQST or IRWD more profitable?
- IRWD runs the higher net margin — AQST at -144.63% versus IRWD at 33.36%.
- How have AQST and IRWD total returns compared?
- Over the past 5 years, AQST delivered 2.24% and IRWD delivered -22.82% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Ironwood Pharmaceuticals P/E ratioAquestive Therapeutics ROEIronwood Pharmaceuticals ROEAquestive Therapeutics operating marginIronwood Pharmaceuticals operating marginAquestive Therapeutics revenue growthIronwood Pharmaceuticals revenue growthAquestive Therapeutics free cash flowIronwood Pharmaceuticals free cash flow
Aquestive Therapeutics & Ironwood Pharmaceuticals appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.