Aptevo Therapeutics Inc. (APVO) vs Mustang Bio, Inc. (MBIO)

A side-by-side comparison of Aptevo Therapeutics Inc. and Mustang Bio, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

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Total return — APVO vs MBIO

growth of $100 · dividends reinvested · last 9y
APVO -100.0% (-82.6%/yr)MBIO -100.0% (-65.9%/yr)MBIO compounded faster over this window
Log scale — wide-divergence pair
000001101001kStart $1002019202120232025$0$0
APVO MBIO

APVO vs MBIO: by the numbers

  • •APVO is the larger company ($4M vs $3M market cap).

Metrics side by side

Valuation

MetricAPVOMBIO
P/B ratio0.660.46

Profitability

MetricAPVOMBIO
Gross margin0.00%0.00%
Operating margin0.00%0.00%
Net margin0.00%0.00%
ROE-437.15%-40.20%
ROIC-288.14%-45.77%

Growth (annualized)

MetricAPVOMBIO
Total return CAGR (5Y)-95.30%-80.80%

Frequently asked

How have APVO and MBIO total returns compared?
Over the past 5 years, APVO delivered -95.30% and MBIO delivered -80.80% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.