Aptevo Therapeutics Inc. (APVO) vs Ernexa Therapeutics Inc. (ERNA)

A side-by-side comparison of Aptevo Therapeutics Inc. and Ernexa Therapeutics Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

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Total return — APVO vs ERNA

growth of $100 · dividends reinvested · last 10y
APVO -100.0% (-80.3%/yr)ERNA -100.0% (-65.1%/yr)ERNA compounded faster over this window
Log scale — wide-divergence pair
0000001101001kStart $10020182020202220242026$0$0
APVO ERNA

APVO vs ERNA: by the numbers

  • •APVO is the larger company ($4M vs $4M market cap).

Metrics side by side

Valuation

MetricAPVOERNA
P/B ratio0.661.21

Profitability

MetricAPVOERNA
Gross margin0.00%0.00%
Operating margin0.00%0.00%
Net margin0.00%0.00%
ROE-437.15%-383.03%
ROIC-288.14%-346.94%

Growth (annualized)

MetricAPVOERNA
Total return CAGR (5Y)-95.30%-86.83%

Frequently asked

How have APVO and ERNA total returns compared?
Over the past 10 years, APVO delivered -80.35% and ERNA delivered -65.14% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.