Aptevo Therapeutics Inc. (APVO) vs Dermata Therapeutics, Inc. (DRMA)

A side-by-side comparison of Aptevo Therapeutics Inc. and Dermata Therapeutics, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

Compare

Total return — APVO vs DRMA

growth of $100 · dividends reinvested · last 5y
APVO -100.0% (-95.4%/yr)DRMA -100.0% (-84.5%/yr)DRMA compounded faster over this window
Log scale — wide-divergence pair
000001101001kStart $10020222023202420252026$0$0
APVO DRMA

APVO vs DRMA: by the numbers

  • •DRMA is the larger company ($5M vs $4M market cap).

Metrics side by side

Valuation

MetricAPVODRMA
P/B ratio0.671.32

Profitability

MetricAPVODRMA
Gross margin0.00%0.00%
Operating margin0.00%0.00%
Net margin0.00%0.00%
ROE-437.15%-239.95%
ROIC-288.14%-246.61%

Growth (annualized)

MetricAPVODRMA
Total return CAGR (5Y)-95.30%-83.90%

Frequently asked

How have APVO and DRMA total returns compared?
Over the past 5 years, APVO delivered -95.30% and DRMA delivered -83.90% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.