Aptevo Therapeutics Inc. (APVO) vs Cadrenal Therapeutics, Inc. Common Stock (CVKD)
A side-by-side comparison of Aptevo Therapeutics Inc. and Cadrenal Therapeutics, Inc. Common Stock across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
APVO
Aptevo Therapeutics Inc.
$1.85HealthcareDelayed quote: Oct 6, 2026, 11:59 AM EDT
CVKD
Cadrenal Therapeutics, Inc. Common Stock
$0.94HealthcareDelayed quote: Oct 6, 2026, 12:00 PM EDT
Total return — APVO vs CVKD
growth of $100 · dividends reinvested · last 4yAPVO -100.0% (-96.5%/yr)CVKD -98.5% (-64.8%/yr)CVKD compounded faster over this window
Log scale — wide-divergence pair
APVO CVKD
APVO vs CVKD: by the numbers
- •APVO is the larger company ($4M vs $3M market cap).
Metrics side by side
Valuation
| Metric | APVO | CVKD |
|---|---|---|
| P/B ratio | 0.67 | 0.82 |
Profitability
| Metric | APVO | CVKD |
|---|---|---|
| Gross margin | 0.00% | 0.00% |
| Operating margin | 0.00% | 0.00% |
| Net margin | 0.00% | 0.00% |
| ROE | -437.15% | -282.13% |
| ROIC | -288.14% | -284.81% |
Growth (annualized)
| Metric | APVO | CVKD |
|---|---|---|
| Total return CAGR (5Y) | -95.30% | N/A |
Go deeper
Dig into the metrics
Aptevo Therapeutics ROECadrenal Therapeutics, Inc. Common Stock ROEAptevo Therapeutics operating marginCadrenal Therapeutics, Inc. Common Stock operating marginAptevo Therapeutics revenue growthCadrenal Therapeutics, Inc. Common Stock revenue growthAptevo Therapeutics free cash flowCadrenal Therapeutics, Inc. Common Stock free cash flow
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.