Aptevo Therapeutics Inc. (APVO) vs CollPlant Biotechnologies Ltd. (CLGN)

A side-by-side comparison of Aptevo Therapeutics Inc. and CollPlant Biotechnologies Ltd. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

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Total return — APVO vs CLGN

growth of $100 · dividends reinvested · last 9y
APVO -100.0% (-84.1%/yr)CLGN -96.2% (-30.5%/yr)CLGN compounded faster over this window
Log scale — wide-divergence pair
0000001101001kStart $1002020202220242026$0$4
APVO CLGN

APVO vs CLGN: by the numbers

  • •CLGN is the larger company ($4M vs $4M market cap).
  • •Both run net losses; APVO's is the smaller (0.00% vs -3934.91% net margin).

Metrics side by side

Valuation

MetricAPVOCLGN
P/S ratioN/A13.60
P/B ratio0.661.47

Profitability

MetricAPVOCLGN
Gross margin0.00%26.32%
Operating margin0.00%-484.31%
Net margin0.00%-3934.91%
ROE-437.15%-424.89%
ROIC-288.14%-221.32%

Growth (annualized)

MetricAPVOCLGN
Revenue CAGR (5Y)N/A-56.28%
Total return CAGR (5Y)-95.30%-53.69%

Frequently asked

How have APVO and CLGN total returns compared?
Over the past 5 years, APVO delivered -95.30% and CLGN delivered -53.69% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.