AN2 Therapeutics, Inc. (ANTX) vs Zentalis Pharmaceuticals, Inc. (ZNTL)

A side-by-side comparison of AN2 Therapeutics, Inc. and Zentalis Pharmaceuticals, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

Compare
AN2 Therapeutics, Inc. logo
ANTX
AN2 Therapeutics, Inc.
$183M
$5.07HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT
Zentalis Pharmaceuticals, Inc. logo
ZNTL
Zentalis Pharmaceuticals, Inc.
$190M
$2.67HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT

Total return — ANTX vs ZNTL

growth of $100 · dividends reinvested · last 5y
ANTX -63.6% (-18.3%/yr)ZNTL -94.0% (-43.0%/yr)ANTX compounded faster over this window
Log scale — wide-divergence pair
1101001kStart $1002023202420252026$36$6
ANTX ZNTL

ANTX vs ZNTL: by the numbers

  • •ZNTL is the larger company ($190M vs $183M market cap).

Metrics side by side

Valuation

MetricANTXZNTL
P/B ratio2.411.32

Profitability

MetricANTXZNTL
Gross margin0.00%0.00%
Operating margin0.00%0.00%
Net margin0.00%0.00%
ROE-47.78%-121.76%
ROIC-51.01%-105.17%

Growth (annualized)

MetricANTXZNTL
Total return CAGR (5Y)N/A-47.34%

Go deeper

Full ANTX analysisFull ZNTL analysisInteractive comparison tool

Dig into the metrics

AN2 Therapeutics ROEZentalis Pharmaceuticals ROEAN2 Therapeutics operating marginZentalis Pharmaceuticals operating marginAN2 Therapeutics revenue growthZentalis Pharmaceuticals revenue growthAN2 Therapeutics free cash flowZentalis Pharmaceuticals free cash flow

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.