Annexon, Inc. (ANNX) vs Olema Pharmaceuticals, Inc. (OLMA)

A side-by-side comparison of Annexon, Inc. and Olema Pharmaceuticals, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

Compare

Total return — ANNX vs OLMA

growth of $100 · dividends reinvested · last 6y
ANNX -82.3% (-25.1%/yr)OLMA -83.2% (-25.7%/yr)ANNX compounded faster over this window
050100150Start $100202120222023202420252026$18$17
ANNX OLMA

ANNX vs OLMA: by the numbers

  • •OLMA is the larger company ($688M vs $665M market cap).

Metrics side by side

Valuation

MetricANNXOLMA
P/B ratio3.571.60

Profitability

MetricANNXOLMA
Gross margin0.00%0.00%
Operating margin0.00%0.00%
Net margin0.00%0.00%
ROE-108.93%-47.51%
ROIC-101.43%-50.92%

Growth (annualized)

MetricANNXOLMA
Total return CAGR (5Y)-26.29%-21.50%

Frequently asked

How have ANNX and OLMA total returns compared?
Over the past 5 years, ANNX delivered -26.29% and OLMA delivered -21.50% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.